Isolation and characterization of a novel H10N2 avian influenza virus from a domestic duck in Eastern China
文献类型： 外文期刊
作者： Wu, Haibo 1 ; Lu, Kufeng; Wu, Xiaoxin 1 ; Peng, Xiaorong 1 ; Xu, Lihua; Cheng, Linfang 1 ; Lu, Xiangyun 1 ; Jin, Ch 1 ;
作者机构： 1.Zhejiang Univ, Sch Med, Affiliated Hosp 1, State Key Lab Diag & Treatment Infect Dis, Hangzhou 310003, Zhejiang, Peoples R China
2.Zhejiang Univ, Sch Med, Affiliated Hosp 1, State Key Lab Diag & Treatment Infect Dis, Hangzhou 310003, Zhejiang, P
关键词： Avian influenza viruses;H10N2;Genetic analysis;Domestic ducks;Reassortment
期刊名称：INFECTION GENETICS AND EVOLUTION （ 影响因子：3.342； 五年影响因子：3.188 ）
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收录情况： SCI
摘要： During the surveillance for avian influenza viruses (AIVs) in live poultry markets (LPMs) in Eastern China, in 2013, an H10N2 AIV was isolated from a domestic duck. Phylogenetic analysis showed that this strain received its genes from H10, H1 and H7 AlVs of wild birds in China. The virulence of this strain was examined in chickens and mice, and was found to be low pathogenic in chickens but demonstrated moderate pathogenicity in mice. These results suggest that active surveillance of AIVs in LPMs should be used in an early warning system for avian influenza outbreaks. (C) 2014 Elsevier B.V. All rights reserved.
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