A target-induced three-way G-quadruplex junction for 17 beta-estradiol monitoring with a naked-eye readout
文献类型： 外文期刊
作者： Chen, Junhua 1 ; Wen, Junlin 1 ; Yang, Guiqin 1 ; Zhou, Shungui 1 ;
作者机构： 1.Guangdong Inst Ecoenvironm & Soil Sci, Guangdong Key Lab Agr Environm Pollut Integrated, Guangzhou 510650, Guangdong, Peoples R China
期刊名称：CHEMICAL COMMUNICATIONS （ 影响因子：6.222； 五年影响因子：6.008 ）
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收录情况： SCI
摘要： A label-free and enzyme-free three-way G-quadruplex junction sensing system for the amplified detection of 17 beta-estradiol has been constructed by the ingenious coupling of split G-quadruplex DNAzyme with toehold-mediated strand displacement. The biosensor is ultrasensitive, enabling the visual detection of 17 beta-estradiol concentrations as low as 1 fM without instrumentation.
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