文献类型： 外文期刊
作者： Liu, Xin 1 ; Zhang, Junsheng 1 ; Liu, Qiao 1 ; Tang, Guihua 1 ; Wang, Hongsheng 1 ; Fan, Chengqi 2 ; Yin, Sheng 1 ;
作者机构： 1.Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangzhou 510006, Guangdong, Peoples R China
2.Chinese Acad Fishery Sci, East China Sea Fisheries Res Inst, Shanghai 200090, Peoples R China
关键词： Sarcophyton elegans;cembranoids;antimigratory activity
期刊名称：MOLECULES （ 影响因子：4.411； 五年影响因子：4.587 ）
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收录情况： SCI
摘要： Four new cembranoids, sarcophelegans A-D (1-4) and six known analogues (5-10) were isolated from the South China Sea soft coral Sarcophyton elegans. Their structures were elucidated through detailed spectroscopic analysis, and the absolute configuration of 1 was confirmed by single-crystal X-ray diffraction. The antimigratory potential of compounds 1-10 were evaluated and compounds 2 and 6 were found to inhibit human breast tumor MDA-MB-231 cell migration at 10 mu M.
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