您好，欢迎访问湖北省农业科学院 机构知识库！
湖北省农业科学院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

mrskn7, a putative response regulator gene of Monascus ruber M7, is involved in oxidative stress response, development, and mycotoxin production

文献类型： 外文期刊

作者： Shao, Yanchun 1 ; Yang, Sha 2 ; Zhang, Zhouwei 3 ; Zhou, Youxiang 4 ; Chen, Fusheng 1 ;

作者机构： 1.Huazhong Agr Univ, Coll Food Sci & Technol, State Key Lab Agr Microbiol, Key Lab Environm Correlat Dietol,Minist Educ, 1 Shizishan St, Wuhan 430070, Hubei Province, Peoples R China

2.Huazhong Agr Univ, Coll Food Sci & Technol, 1 Shizishan St, Wuhan 430070, Hubei Province, Peoples R China

3.Hubei Acad Agr Sci, Inst Proc Agr Prod & Nucl Agr Res, 1 Yaoyuan St, Wuhan 430064, Hubei Province, Peoples R China

4.Hubei Acad Agr Sci, Inst Qual Standard & Testing Technol Agroprod, 1 Yaoyuan St, Wuhan 430064, Hubei Province, Peoples R China

关键词： citrinin;development;Monascus ruber;oxidative stress;response regulator

期刊名称：MYCOLOGIA （ 影响因子：2.696； 五年影响因子：3.089 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： Skn7, a response regulator (RR), is associated with oxidative stress adaptation, hypo-osmotic stress response, fungicide sensitivity, cell wall biosynthesis, cell cycle regulation, sexual mating, and sporulation in many filamentous fungi and yeasts. In this study a Skn7-like protein gene mrskn7 (Monascus ruber skn7) was isolated, sequenced, and disrupted to investigate its function in M. ruber. Bioinformatics predicted that the deduced protein encoded by mrskn7 contained the conserved DNA-binding and signal-receiver domains similar to the Skn7-like protein structure in other filamentous fungi. The Delta mrskn7 strain produced fewer conidia and less mycotoxin, demonstrated increased sensitivity to peroxide but the same level of osmotic resistance to NaCl and glycerol with the wild type. Additionally, cleistothecia observed at different time point showed a different morphology between the wild-type and the Delta mrskn7 strain, suggesting the involvement of mrskn7 in sexual development of M. ruber. These results indicated that mrskn7 plays important roles in asexual and sexual development, the production of mycotoxin as well as regulation of oxidative stress signal in M. Tuber.

  • 相关文献

[1]Identification of Mga1, a G-protein alpha-subunit gene involved in regulating citrinin and pigment production in Monascus ruber M7. Li, Li,Shao, Yanchun,Li, Qi,Yang, Sha,Chen, Fusheng,Shao, Yanchun,Chen, Fusheng,Chen, Fusheng. 2010

[2]Effects of cyclic AMP on development and secondary metabolites of Monascus ruber M-7. Chen, F.,Chen, F.,Lai, Y.,Wang, L.,Qing, L.,Chen, F.. 2011

[3]Identification and role analysis of an intermediate produced by a polygenic mutant of Monascus pigments cluster in Monascus ruber M7. Liu, Jiao,Yi, Tao,Lei, Ming,Liu, Qingpei,Shao, Yanchun,Chen, Fusheng,Zhou, Youxiang,Zhao, Mingming,Chen, Fusheng,Xie, Nana.

[4]Inactivation of the global regulator LaeA in Monascus ruber results in a species-dependent response in sporulation and secondary metabolism. Shao, Yanchun,Li, Mu,Chen, Fusheng,Wang, Xiaohong,Chen, Fusheng,Liu, Qingpei,Cai, Li,Shao, Yanchun,Li, Mu,Wang, Xiaohong,Chen, Fusheng,Zhou, Youxiang.

[5]NAD(+)-dependent HDAC inhibitor stimulates Monascus pigment production but inhibit citrinin. Hu, Yan,Mao, Zejing,Chen, Fusheng,Shao, Yanchun,Zhou, Youxiang,Li, Huihui. 2017

[6]Effects of an alternative oxidase gene on conidia viability under external stresses in Monascus ruber M7. Shao, Yanchun,Li, Qi,Chen, Fusheng,Zhou, Youxiang,Chen, Fusheng. 2017

[7]Effects of glycerol on pigments and monacolin K production by the high-monacolin K-producing but citrinin-free strain, Monascus pilosus MS-1. Feng, Yanli,Shao, Yanchun,Chen, Fusheng,Feng, Yanli,Shao, Yanchun,Chen, Fusheng,Feng, Yanli,Zhou, Youxiang.

[8]A study of fluorescence properties of citrinin in beta-cyclodextrin aqueous solution and different solvents. Chen, Jianbiao,Dong, Lina,Lu, Liang,Chen, Fusheng,Wang, Xiaohong,Zhou, Youxiang,Hu, Dingjin,Chen, Fusheng,Wang, Xiaohong,Chen, Fusheng. 2012

[9]mrflbA, encoding a putative FlbA, is involved in aerial hyphal development and secondary metabolite production in Monascus ruber M-7. Yang, Yishan,Li, Li,Li, Xin,Shao, Yanchun,Chen, Fusheng,Shao, Yanchun,Chen, Fusheng,Chen, Fusheng. 2012

[10]Effects of N management on growth, N-2 fixation and yield of soybean. Gan, YB,Stulen, I,Posthumus, F,van Keulen, H,Kuiper, P. 2002

[11]Spatial Learning and Memory Impairment and Pathological Change in Rats Induced by Acute Exposure to Microcystin-LR. Li, Guangyu,Chen, Nan,Wang, Jianghua,Yan, Wei,Cai, Fei,Li, Cairong.

[12]Physiological Effects and Fluorescence Labeling of Magnetic Iron Oxide Nanoparticles on Citrus (Citrus reticulata) Seedlings. Li, Junli,Hu, Jing,Xiao, Lian,Gan, Qiuliang,Li, Junli,Wang, Yunqiang. 2017

作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：湖北省农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台