Transcriptome Analyses Reveal Lipid Metabolic Process in Liver Related to the Difference of Carcass Fat Content in Rainbow Trout (Oncorhynchus mykiss)
文献类型： 外文期刊
作者： Hu, Guo 1 ; Gu, Wei 1 ; Sun, Peng 1 ; Bai, Qingli 1 ; Wang, Bingqian 1 ;
作者机构： 1.Chinese Acad Fishery Sci, Heilongjiang River Fishery Res Inst, Natl & Local Joint Engn Lab Freshwater Fish Breed, Harbin 150070, Peoples R China
期刊名称：INTERNATIONAL JOURNAL OF GENOMICS （ 影响因子：2.326； 五年影响因子：2.557 ）
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收录情况： SCI
摘要： Excessive accumulation of carcass fat in farm animals, including fish, has a significant impact on meat quality and on the cost of feeding. Similar to farmed animals and humans, the liver can be considered one of the most important organs involved in lipid metabolism in rainbow trout (Oncorhynchus mykiss). RNA-seq based whole transcriptome sequencing was performed to liver tissue of rainbow trout with high and low carcass fat content in this study. In total 1,694 differentially expressed transcripts were identified, including many genes involved in lipid metabolism, such as L-FABP, adiponectin, PPAR-alpha, PPAR-beta, and IGFBP1a. Evidence presented in this study indicated that lipid metabolic process in liver may be related to the difference of carcass fat content. The relevance of PPAR-alpha and PPAR-beta as molecular markers for fat storage in liver should be worthy of further investigation.
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