文献类型： 外文期刊
作者： Zhai, Lijuan 1 ; Sun, Jian 1 ; Zhou, Pengjuan 1 ; Ji, Jingwen 1 ; He, Lili 1 ; Tang, Dong 1 ; Ji, Jinbo 1 ; Yang, Haikang 1 ; Iqbal, Zafar 1 ; Yang, Zhixiang 1 ;
作者机构： 1.Ningxia Acad Agr & Forestry Sci, Ningxia Ctr Organ Synth & Engn Technol, 590 Huanghe East Rd, Yinchuan 750002, Ningxia, Peoples R China
关键词： kukoamine A; natural product; dihydrocaffeic acid; spermine
期刊名称：CHEMISTRY OF NATURAL COMPOUNDS （ 影响因子：0.8； 五年影响因子：0.8 ）
ISSN： 0009-3130
年卷期： 2024 年
页码：
收录情况： SCI
摘要： Kukoamine A has been known for decades as an anti-inflammatory and hypotensive principle of Chinese medicinal plant extract from Lycium root, bark, and fruit. The recent pharmacological significance of this alkaloid makes it a potential therapeutic target for the pharmaceutical industry. We accomplished the synthesis of kukoamine A in a 73% yield over four steps starting from cheaper commercial reagents, ambient reaction conditions, and minimal purification efforts.
- 相关文献
作者其他论文 更多>>
-
Ruthenium-catalyzed reaction of dinitriles with primary alcohols for the synthesis of N-alkylated cyclic β-enaminonitriles
作者：Ma, Wei;Zhao, Qiang;Su, Shibin;Zhang, Weiwei;Yao, Yao;Wang, Pei;Tang, Dong;Zhou, Pengjuan
关键词：N-alkylated cyclic beta-enaminonitriles; aliphatic dinitrile; primary alcohol; ruthenium-catalyzed
-
Base-Catalyzed Cascade Cyclization of Acyl Cyanides and Isocyanates for the Synthesis of Oxazoles
作者：Zhang, Wei;Li, Hongjun;Hou, Jing;Wan, Yaya;Zhou, Pengjuan;Tang, Dong
关键词：Acyl cyanides; Base-promoted; Cyclization reaction; Oxazoles; Isocyanates
-
Electrochemical Selenylation-Induced Oxyselenation of Alkene Derivatives for the Synthesis of β-Hydroxyselenides
作者：Huang, Ruimin;Zhou, Ruichen;Hou, Guoan;Hou, Jing;Wan, Yaya;Zhou, Pengjuan;Tang, Dong
关键词：Diselenides; Electrosynthesis; Oxyselenation; Styrene; beta-Hydroxyselenides
-
Synergism between Surface Engineering and S-Scheme Heterojunctions for Efficient Photocatalytic H2 Evolution
作者：Guo, Xin;Wen, Bo;Liu, Jiayue;Jin, Zhiliang;Tang, Dong;Li, Youji
关键词：
-
Selected Electrosynthesis of 3-Aminopyrazoles from α,β-Alkynic Hydrazones and Secondary Amines
作者：Tang, Dong;Zhang, Wei;Ji, Jingwen;Jiang, Rui;Wan, Yaya;Zhou, Pengjuan;Ma, Wei
关键词：
-
Synthesis of N1-caffeoyl-N10-dihydrocaffeoylspermidine (Scotanamine D)
作者：Ji, Jingwen;Iqbal, Zafar;Sun, Jian;Zhou, Pengjuan;Zhai, Lijuan;He, Lili;Tang, Dong;Ji, Jinbo;Yang, Haikang;Yang, Zhixiang;Li, Liuyan
关键词：N1-caffeoyl-N10-dihydrocaffeoylspermidine; spermidine; alkaloid; yields; medicinally valuable; natural compound; synthesis
-
Electrochemical Selenylation-Induced Annulation of Alkenyl Ureas to Access Cyclic Isoureas
作者：Li, Hongjun;Yang, Jinhui;Tang, Dong;Zhou, Pengjuan;Wan, Yaya;Jiang, Rui
关键词：Alkenyl ureas; Selenylation; Electrochemistry; Cyclic isoureas; C-O/C-Se bond formation
