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Improved methods for mass production of magnetosomes and applications: a review

文献类型: 外文期刊

作者: Basit, Abdul 1 ; Wang, Jiaojiao 1 ; Guo, Fangfang 3 ; Niu, Wei 1 ; Jiang, Wei 1 ;

作者机构: 1.China Agr Univ, Coll Biol Sci, State Key Lab Agrobiotechnol, Beijing 100193, Peoples R China

2.Univ Okara, Dept Microbiol, Fac Life Sci, Okara 56130, Pakistan

3.Beijing Acad Agr & Forestry Sci, Inst Anim Husb & Vet Med, Beijing Key Lab Prevent & Control Infect Dis Live, Beijing, BJ, Peoples R China

关键词: Magnetosome biosynthesis; high-yield; cell growth; culture conditions; commercial applications

期刊名称:MICROBIAL CELL FACTORIES ( 影响因子:5.328; 五年影响因子:5.588 )

ISSN:

年卷期: 2020 年 19 卷 1 期

页码:

收录情况: SCI

摘要: Magnetotactic bacteria have the unique ability to synthesize magnetosomes (nano-sized magnetite or greigite crystals arranged in chain-like structures) in a variety of shapes and sizes. The chain alignment of magnetosomes enables magnetotactic bacteria to sense and orient themselves along geomagnetic fields. There is steadily increasing demand for magnetosomes in the areas of biotechnology, biomedicine, and environmental protection. Practical difficulties in cultivating magnetotactic bacteria and achieving consistent, high-yield magnetosome production under artificial environmental conditions have presented an obstacle to successful development of magnetosome applications in commercial areas. Here, we review information on magnetosome biosynthesis and strategies for enhancement of bacterial cell growth and magnetosome formation, and implications for improvement of magnetosome yield on a laboratory scale and mass-production (commercial or industrial) scale.

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