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A multi-omics database of buffaloes from Yangtze valley reveals diversity of water buffalo (Bubalus bubalis)

文献类型: 外文期刊

作者: Shen, Yangyang 1 ; An, Zhenjiang 1 ; Xia, Shuwen 1 ; Ding, Qiang 1 ; Chen, Kunlin 1 ; Miao, Yilong 3 ; Wang, Tao 4 ; Zhong, Jifeng 1 ; Li, Jianbin 5 ; Wang, Xiao 5 ; Wang, Huili 1 ;

作者机构: 1.Jiangsu Acad Agr Sci, Inst Anim Sci, Nanjing 210014, Peoples R China

2.Jiangsu Prov Engn Res Ctr Precis Anim Breeding, Nanjing 210014, Peoples R China

3.Nanjing Agr Univ, Coll Anim Sci & Technol, Nanjing 210095, Peoples R China

4.Guangdong GemPharmatech Co Ltd, Foshan 528000, Peoples R China

5.Shandong Acad Agr Sci, Inst Anim Sci & Vet Med, Jinan 250100, Peoples R China

6.Shandong OX Livestock Breeding Co Ltd, Jinan 250100, Peoples R China

期刊名称:SCIENTIFIC DATA ( 影响因子:6.9; 五年影响因子:8.7 )

ISSN:

年卷期: 2024 年 11 卷 1 期

页码:

收录情况: SCI

摘要: Asian water buffalo (Bubalus bubalis) is the fundamental livestock resource for local rural populations and holds a promising prospect of their milk and meat. Xuyi mountain (XYM) and Haizi (HZ) buffaloes from Yangtze valley comprises of species diversity of Asian water buffaloes. Current multi-omics enables identification of causal genes and elucidation of genetic regulatory mechanisms underlying complex traits in buffaloes. Here, we conducted the integrated analysis of metabolome and metagenome of rumen fluid, transcriptome and metabolome of blood, and whole genome sequence data from XYM (n = 7) and HZ (n = 10) male buffaloes. Our results revealed the apparent diversity of multi-layer omics profiles between two buffalo species. The built-up multi-omics database supports the discoveries of diversity in Asian water buffalo and potentially serves valuable resources for studying causal regulatory variants and their mechanisms.

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