文献类型： 外文期刊
作者： Yang, Chengmin 1 ; Chen, Huiqin 2 ; Gao, Shuyi 1 ; Wang, Hao 2 ; He, Di 1 ; Cai, Caihong 2 ; Mei, Wenli 2 ; Liu, Shoubai 1 ; Dai, Haofu 2 ;
作者机构： 1.Hainan Univ, Sch Forestry, Key Lab Genet & Germplasm Innovat Trop Special For, Minist Educ,Hainan Key Lab Biol Trop Specif Orname, Haikou 570228, Peoples R China
2.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Hainan Key Lab Res & Dev Nat Prod Li Folk Med, Haikou 570228, Peoples R China
关键词： Croton laui; Euphorbiaceae; Diterpenoids; Cytotoxic activity
期刊名称：PHYTOCHEMISTRY LETTERS （ 影响因子：1.7； 五年影响因子：1.8 ）
ISSN： 1874-3900
年卷期： 2023 年 53 卷
页码：
收录情况： SCI
摘要： Three new diterpenoids, including one trachylobane (1) and two labdanes (2-3), were isolated from the aerial parts of Croton laui. Their structures were determined by analysis of their spectroscopic data. The absolute configuration of compound 1 was established by single-crystal X-ray diffraction analysis. Compounds 1-3 were assessed for cytotoxicity against A549, BEL-7402, SGC-7901, and Hela cell lines by the MTT assay. Compound 1 showed weak activity against the four human cancer cell lines with IC50 values of 36.09-93.94 mu M.
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