Structural characteristics and anti-inflammatory activity of UV/H2O2-treated algal sulfated polysaccharide from Gracilaria lemaneiformis
文献类型： 外文期刊
作者： Gong, Yufeng 1 ; Ma, Yongxuan 2 ; Cheung, Peter Chi-Keung 4 ; You, Lijun 1 ; Liao, Lan 6 ; Pedisic, Sandra 7 ; Kulikou 1 ;
作者机构： 1.South China Univ Technol, Sch Food Sci & Engn, 381 Wushan Rd, Guangzhou 510640, Guangdong, Peoples R China
2.Guangdong Acad Agr Sci, Sericultural & Agrifood Res Inst, Guangzhou 510610, Guangdong, Peoples R China
3.Guangzhou Liheng Clin Nutr Co Ltd, Guangzhou 510610, Guangdong, Peoples R China
4.Chinese Univ Hong Kong, Sch Life Sci, Food & Nutr Sci Program, Hong Kong, Peoples R China
5.Overseas Expertise Intro Ctr Discipline Innovat F, Guangzhou 510640, Guangdong, Peoples R China
6.Foshan Univ, Coll Food Sci & Technol, Dept Food Sci, Foshan 528000, Guangdong, Peoples R China
7.Univ Zagreb, Fac Food Technol & Biotechnol, Prolaz Kasandrica 6, Zadar 23000, Croatia
8.Natl Acad Sci Belarus, Inst Chem New Mat, 36F Skaryna Str, Minsk 220141, BELARUS
关键词： Gracilaria lemaneiformis; Sulfated polysaccharide; UV; Molecular weight; Inflammation
期刊名称：FOOD AND CHEMICAL TOXICOLOGY （ 影响因子：6.025； 五年影响因子：5.847 ）
ISSN： 0278-6915
年卷期： 2021 年 152 卷
页码：
收录情况： SCI
摘要： The study aimed to study the effects on structural characteristics and anti-inflammatory activities of algal sulfated polysaccharides isolated from Gracilaria lemaneiformis (GLP) after a combined treatment of UV irradiation (average irradiance of 6500 mJ/cm(2)) and H2O2 (50 mmol/L) for various time periods up to 60 min. After a 30-min treatment, the molecular weight and particle size of GLP was decreased by 15 and 2.6 fold, respectively with small but significant decrease in the contents of total sugars, uronic acids and proteins. There seemed to have no starch and the presence of longer side chains of branches in the GLP samples before and after UV/H2O2 treatment based on the I-2-KI assay. Scanning electron microscope and atomic force microscope analysis confirmed that the UV/H2O2 treatment could modify the surface morphology of GLP. GLP treated for 5 min possessed the strongest in vitro anti-inflammatory activity by inhibiting the production of nitric oxide, tumor necrosis factor- a and interleukin-6 by 60.49%, 62.81% and 36.29%, respectively in IEC-6 cells when compared to the model. Therefore, UV/H2O2 treatment had the potential to enhance the anti-inflammatory activity of algal sulfated polysaccharides.
- 相关文献
作者其他论文 更多>>
-
Comparison of different longan polysaccharides during gut Bacteroides fermentation
作者：Wang, Jidongtian;Ma, Yongxuan;Xu, Xiang;Huang, Guitao;Zhang, Ruifen;Jia, Xuchao;Dong, Lihong;Deng, Mei;Zhang, Mingwei;Huang, Fei;Zhang, Mingwei
关键词：Bacteroides; Fermentation properties; Longan polysaccharide
-
Effects of UV/H2O2 degradation and step gradient ethanol precipitation on Sargassum fusiforme polysaccharides: Physicochemical characterization and protective effects against intestinal epithelial injury
作者：Yao, Wanzi;Liu, Mengyuan;Chen, Xiaoyong;You, Lijun;Yao, Wanzi;Liu, Mengyuan;Chen, Xiaoyong;You, Lijun;Ma, Yongxuan;Hileuskaya, Kseniya
关键词：Sargassum fusiforme; Polysaccharides; UV/H2O2; IEC-6 cells; Intestinal barrier function; Intestinal inflammation
-
Structure determination, bitterness evaluation and hepatic gluconeogenesis inhibitory activity of triterpenoids from the Momordica charantia fruit
作者：Deng, Yuanyuan;Ma, Yongxuan;Liu, Huijuan;Zhang, Yan;Wei, Zhencheng;Liu, Guang;Tang, Xiaojun;Jia, Xuchao
关键词：Momordica charantia; Bitter melon; Triterpenoids; Bitterness; Gluconeogenesis
-
Hydrolyzed Bound Phenolics from Rice Bran Alleviate Hyperlipidemia and Improve Gut Microbiota Dysbiosis in High-Fat-Diet Fed Mice
作者：Zhao, Guanghe;Zhang, Ruifen;Huang, Fei;Dong, Lihong;Liu, Lei;Jia, Xuchao;Chi, Jianwei;Ma, Yongxuan;Deng, Mei;Chen, Yanxia;Ma, Qin;Zhang, Mingwei;Zhao, Guanghe
关键词：rice bran; hydrolyzed bound phenolics; lipid metabolism; gut microbiota
-
Effects of different extraction methods on contents, profiles, and antioxidant abilities of free and bound phenolics of Sargassum polycystum from the South China Sea
作者：Wu, Yujiao;Gao, Heqi;Wang, Yuxi;Peng, Ziting;Xiao, Juan;Zhong, Qiuping;Guo, Zhiqiang;Ma, Yongxuan;Zhang, Ruifen;Zhang, Mingwei;Wu, Qian
关键词：antioxidant ability; bound phenolic; free phenolic; Sargassum polycystum; seaweed
-
Rice bran-modified wheat gluten nanoparticles effectively stabilized pickering emulsion: An interfacial antioxidant inhibiting lipid oxidation
作者：Wang, Zhiming;Zhang, Mingwei;Wang, Zhiming;Ma, Yongxuan;Deng, Yuanyuan;Wei, Zhencheng;Zhang, Yan;Tang, Xiaojun;Li, Ping;Zhao, Zhihao;Zhou, Pengfei;Liu, Guang;Zhang, Mingwei;Chen, Hualei
关键词：Polyphenols; Conjugate particles; Pickering stabilizer; Emulsion gels; Lipid antioxidant
-
In vitro fermentation characteristics of polysaccharide from Sargassum fusiforme and its modulation effects on gut microbiota
作者：Kong, Qiuhong;You, Lijun;Zhang, Ruifen;Ma, Yongxuan;You, Lijun;Ma, Yongxuan;Liao, Lan;Pedisic, Sandra
关键词：Sargassum fusiforme polysaccharide (SFP); Structural characteristics; Fermentation; Short chain fatty acids (SCFAs); Gut microbiota
