您好，欢迎访问广东省农业科学院 机构知识库！
广东省农业科学院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Polymorphisms of the IGFIR gene and their genetic effects on chicken early growth and carcass traits

文献类型： 外文期刊

作者： Lei, Mingming 1 ; Peng, Xia 1 ; Zhou, Min 1 ; Luo, Chenglong 1 ; Nie, Qinghua 1 ; Zhang, Xiquan 1 ;

作者机构： 1.S China Agr Univ, Coll Anim Sci, Dept Anim Genet Breeding & Reprod, Guangzhou 510642, Guangdong, Peoples R China

2.Guangdong Acad Agr Sci, Inst Anim Sci, Guangzhou 510640, Guangdong, Peoples R China

期刊名称：BMC GENETICS （ 影响因子：2.797； 五年影响因子：3.263 ）

ISSN： 1471-2156

年卷期： 2008 年 9 卷

页码：

收录情况： SCI

摘要： Background: The insulin-like growth factor I receptor (IGFIR) has an important effect on growth, carcass, and meat quality traits in many species. However, few studies on associations of the IGFIR gene with growth and carcass traits have been reported in chickens. The objectives of the present study were to study the associations of the IGFIR gene with chicken early growth and carcass traits using a neutral test, variation scan of the gene, genetic diversity, linkage disequilibrium and association analyses. Results: The tree generated from the amino acid sequences of 15 species showed that the IGFIR gene was conservative in the whole evolution among the mammalian animals and chickens. In a total of 10,818 bp of sequence, 70 single nucleotide polymorphisms were identified in the chicken IGFIR gene. The allelic and genotypic frequency distribution, genetic diversity and linkage disequilibrium of 18 single nucleotide polymorphisms ( SNPs) in the Xinghua and White Recessive Rock chickens showed that six of them were possibly associated with growth traits. Association analyses showed that the A17299834G SNP was significantly associated with chicken carcass body weight, eviscerated weight with giblets, eviscerated weight, body weights at 28, 35, and 56 d of age, leg length at 56 d of age, and daily weight gain at 0-4 weeks. The haplotypes of the A17307750G and A17307494G were associated with early growth traits. The haplotypes of the A17299834G and C17293932T were significantly associated with most of the early growth traits and carcass traits. Conclusion: There were rich polymorphisms in the chicken IGFIR gene. Several SNPs associated with chicken early growth traits and carcass traits were identified in the IGFIR gene by genetic diversity, linkage disequilibrium, and association analyses in the present study.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：广东省农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台