Synthesis and Biological Activities of Some Novel (E)-Alpha-(methoxyimino) benzeneacetate Derivatives with Modified 1,2,4-Triazole Moiety
文献类型： 外文期刊
作者： Wang, Xianyou 1 ; Wang, Hua 2 ; Chen, Peiyun 1 ; Pang, Yanping 1 ; Zhao, Zhilei 1 ; Wu, Guangchen 1 ;
作者机构： 1.Hebei Univ, Coll Qual & Tech Supervis, Baoding 071002, Peoples R China
2.Hubei Acad Agr Sci, Inst Plant Protect & Soil Fertilizer, Wuhan 430064, Peoples R China
期刊名称：JOURNAL OF CHEMISTRY （ 影响因子：2.506； 五年影响因子：2.726 ）
ISSN： 2090-9063
年卷期： 2014 年
页码：
收录情况： SCI
摘要： To find new strobilurin analogues with high activity against resistant pathogens, a series of (E)-alpha-(methoxyimino) benzeneacetate derivatives containing 1,2,4-triazole Schiff base side chain were designed and synthesized. Their structures were confirmed by IR, H-1 NMR, and C-13 NMR, ESI-HRMS, or elemental analyses. Bioassays indicated that most of the target compounds showed moderate to good fungicidal activities against Rhizoctonia solani, Botrytis cinerea Pers., Fusarium graminearum, Cotton rhizoctoniosis, and Blumeria graminis. For example, compounds 6g and 6j exhibited promising antifungal activity against Rhizoctonia solani, Botrytis cinerea Pers., and Fusarium graminearum. Compounds 6c, 6l, and 6m had higher fungicidal activities against Blumeria graminis at the concentration of 50 mu g/mL; inhibitory rate is 91.41%, 92.13%, and 91.77%, respectively.
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