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A new cytotoxic 2-(2-phenylethyl)chromone from Chinese eaglewood

文献类型: 外文期刊

作者: Liu, Jun 1 ; Wu, Jiao 1 ; Zhao, You Xing 2 ; Deng, Yuan Yuan 1 ; Mei, Wen Li 1 ; Dai, Hao Fu 1 ;

作者机构: 1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China

2.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China

关键词: Chinese eaglewood;Aquilaria sinensis;Chromone;Cytotoxicity

期刊名称:CHINESE CHEMICAL LETTERS ( 影响因子:6.779; 五年影响因子:4.558 )

ISSN: 1001-8417

年卷期: 2008 年 19 卷 8 期

页码:

收录情况: SCI

摘要: A new compound 8-chloro-5,6,7-trihydroxy-2-(3-hydroxy-4-methoxyphenethyl)-5,6,7,8-tetrahydro-4H-chromen-4-one (1) was isolated from the Chinese eaglewood [Aquilaria sinensis (Lour.) Gilg]. Its structure was elucidated on the basis of spectral data. Compound 1 showed cytotoxicity against human gastric cancer cell line (SGC-7901) in vitro by MTT method with the IC(50) value of 14.6 mu g/mL. (C) 2008 Wen Li Mei. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

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