文献类型： 外文期刊
作者： Liu, Rongchang 1 ; Sun, Minhua 3 ; Lan, Qin 1 ; Zhang, Jiaxue 1 ; Liang, Qizhang 1 ; Fu, Guanghua 1 ; Liao, Ming 2 ; Huang, Yu 1 ;
作者机构： 1.Fujian Acad Agr Sci, Inst Anim Husb & Vet Med, Fujian Prov Key Lab Avian Dis Control & Prevent, Fuzhou, Peoples R China
2.South China Agr Univ, Coll Vet Med, Natl & Reg Joint Engn Lab Medicament Zoonosis Prev, Guangdong Prov Key Lab Zoonosis Prevent & Control, Guangzhou, Peoples R China
3.Guangdong Acad Agr Sci, Inst Anim Hlth, Key Lab Prevent & Control Avian Influenza & Other, Minist Agr & Rural Affairs, Guangzhou, Peoples R China
4.Zhongkai Univ Agr & Engn, Key Lab Livestock Dis Prevent & Treatment Guangdon, Guangzhou, Peoples R China
期刊名称：TRANSBOUNDARY AND EMERGING DISEASES （ 影响因子：4.3； 五年影响因子：4.3 ）
ISSN： 1865-1674
年卷期： 2024 年 2024 卷
页码：
收录情况： SCI
摘要： In April 2022, a novel Goose adenovirus (GoAdV) isolated from diseased Lion head gooses exhibiting swelling and hemorrhage of liver and kidney, accumulation of fluid in pericardial, in Fujian province of China. The GoAdV was propagated in goose embryo fibroblasts (GEFs), the morphological properties of the virions were studied by electron microscopy, and the full genome sequence was determined and analyzed. The results revealed that the infected cells became round and clustered like grapes, virions accumulated and were arranged in crystal lattice formations in the nucleus of GEFs with a diameter of similar to 80 nm. The new isolate (named CH-FJZZ-202201) has a viral genome size of 43,480 bp and shared 96.69% sequence identity with GoAdV-4 (P29), representing the species Goose aviadenovirus A. Phylogenetic analysis showed that CH-FJZZ-202201 was in the same genetic evolutionary branch with the viruses of Aviadenovirus and was the closest relative to GoAdV-4 P29/Hungary. This is the first report of the GoAdV-4 outside of Hungary, indicating the reemergence of new AdV strains in China.
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