Genetic polymorphisms in SIRT5 gene and their association with carcass traits in Congjiang Xiang pigs
文献类型： 外文期刊
作者： Zhang, Xiong 1 ; Wang, Jing 1 ; Zhao, Chunping 1 ; Zhang, Jing 1 ;
作者机构： 1.Guizhou Acad Agr Sci, Inst Anim Husb & Vet Sci, Guiyang, Peoples R China
关键词： carcass traits; Congjiang Xiang pig; SIRT5; SNP
期刊名称：REVISTA BRASILEIRA DE ZOOTECNIA-BRAZILIAN JOURNAL OF ANIMAL SCIENCE （ 影响因子：1.0； 五年影响因子：1.4 ）
ISSN： 1516-3598
年卷期： 2024 年 53 卷
页码：
收录情况： SCI
摘要： This study was conducted to investigate the polymorphism of the silence information regulator 5 ( SIRT5 ) gene in 103 Congjiang Xiang pigs from Southwest China. We searched for SNP (single nucleotide polymorphism) loci of SIRT5 gene through sequence alignment and PCR. We obtained nine SNP loci: g.14135 A>C (intron 6), g.14247 C>A (intron 6), g.14305 C>T (exon 7), g.14335 C>T (exon 7), g.16603 T>C (intron 7), g.16613 T>C (intron 7), g.16800 G>A (intron 7), g.16812 C>G (intron 7), and g.16916 A>G (exon 8). Further analysis of SNP genotypes associated with the carcass traits of skin thickness, backfat thickness, and eye muscle area was carried out in pigs. We found that the genotypes g.14305 C>T (CC) and g.16812 C>G (CG) had certain advantages for improving the carcass traits of Congjiang Xiang pigs. The haplotype combination of the SIRT5 gene that improved skin thickness was H2H3:CCGGCTCA. These results may provide empirical support for molecular-based breeding of carcass traits in Congjiang Xiang pigs.
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