文献类型： 会议论文

第一作者： Helena Carstensen

作者： Helena Carstensen ¹ ; Eva Z. Hesselkilde ¹ ; Jorgen K. Kanters ² ; Steen Pehrson ³ ; Maria Mathilde Haugaard ¹ ; Thomas Jespersen ¹ ; Rikke Buhl ¹ ;

作者机构： 1.Department of Large Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Taastrup, Denmark

2.Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

3.Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Copenhagen, Denmark

会议名称： Conference of the American College of Veterinary Internal Medicine

主办单位：

页码： 228-

摘要： Atrial fibrillation (AF) is the most common pathological arrhythmia diagnosed in horses. Due to the adverse effects encountered when treating with quinidine sulphate we wanted to improve the medical treatment of AF. In this study we aimed to evaluatethe effects of the antiarrhythmic compounds dofetilide and ranolazine in the equine heart. Furthermore, we hypothesized that the use of a combination of two antiarrhythmic compounds with distinct mechanisms would allow us to use lower doses of each compound and thereby minimize the risk of adverse effects.

分类号： S85-532