61Single- cell profiling of African swine fever virus disease in the pig spleen reveals viral and host dynamics

作者： Zhu, Zixiang; Mao, Ruoqing; Liu, Baohong; Liu, Huanan; Shi, Zhengwang; Zhang, Kunpeng; Liu, Huisheng; Zhang, Danyang; Liu, Jia; Zhao, Zhenxiang; Li, Kangli; Yang, Fan; Cao, Weijun; Zhang, Xiangle; Shen, Chaochao; Sun, Dehui; Tian, Hong; Ru, Yi; Feng, Tao; He, Jijun; Guo, Jianhong; Zhang, Keshan; Zhang, Shilei; Zheng, Haixue; Mao, Ruoqing; Liu, Huanan; He, Jijun; Guo, Jianhong; Zheng, Haixue; Liu, Huanan; Shi, Zhengwang; Zhang, Xiangle; Shen, Chaochao; He, Jijun; Guo, Jianhong; Zheng, Haixue; Wang, Liyuan; Tang, Zhonglin; Ding, Chan; Han, Jun; SCI

机构： Lanzhou Univ, Chinese Acad Agr Sci, State Key Lab Anim Dis Control & Prevent, Coll Vet Med,Lanzhou Vet Res Inst, Lanzhou 730046, Peoples R China; Chinese Acad Agr Sci, Lanzhou Vet Res Inst, African Swine Fever Reg Lab China, Lanzhou 730046, Peoples R China; Gansu Prov Res Ctr Basic Disciplines Pathogen Biol, Lanzhou 730046, Peoples R China; Chinese Acad Agr Sci, Agr Genom Inst Shenzhen, Shenzhen Branch, Guangdong Lab Lingnan Modern Agr, Shenzhen 518124, Peoples R China; Chinese Acad Agr Sci, Shanghai Vet Res Inst, Shanghai 200241, Peoples R China; China Agr Univ, Coll Vet Med, Minist Agr & Rural Affairs, Key Lab Anim Epidemiol, Beijing 100193, Peoples R China;

来源：PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

关键词： African swine fever virus; single- cell RNA sequencing; host antiviral response; monocytes; cellular tropism

年份：2024

62Picornavirus VP3 protein induces autophagy through the TP53-BAD-BAX axis to promote viral replication

作者： Mao, Ruoqing; Zhu, Zixiang; Yang, Fan; Sun, Dehui; Zhou, Xiaoli; Cao, Weijun; Qin, Xiaodong; Dang, Wen; Liu, Huanan; Tian, Hong; Zhang, Keshan; Liu, Xiangtao; Zheng, Haixue; Wu, Qingfeng; SCI

机构： Lanzhou Univ, Lanzhou Vet Res Inst, Chinese Acad Agr Sci, Coll Vet Med,State Key Lab Anim Dis Control & Prev, 1 Xujiaping Rd, Lanzhou 730046, Peoples R China; Chinese Acad Sci, Inst Modern Phys, Ctr Tech Dev & Anal Serv, Anal & Test Grp, Lanzhou, Peoples R China;

来源：AUTOPHAGY

关键词： Autophagy; picornavirus; replication; TP53-BAD-BAX axis; VP3

年份：2024

63Deletion of a 7-amino-acid region in the porcine epidemic diarrhea virus envelope protein induces higher type I and III interferon responses and results in attenuation in vivo

作者： Li, Zhiwei; Han, Weiguo; Guo, Xuyang; Feng, Yingtong; Xu, Lele; Wang, Xinglong; Xiao, Shuqi; Li, Zhiwei; Ma, Zhiqian; Chang, Chuanzhe; Li, Yang; Zheng, Zifang; Zheng, Haixue; Xiao, Shuqi; SCI

机构： Northwest A&F Univ, Coll Vet Med, Yangling, Shaanxi, Peoples R China; Lanzhou Univ, Chinese Acad Agr Sci, Coll Vet Med, State Key Lab Anim Dis Control & Prevent,Lanzhou, Lanzhou, Gansu, Peoples R China;

来源：JOURNAL OF VIROLOGY

关键词： PEDV; coronavirus; envelope; reverse genetic analysis; virulence factor; interferon; the molecular basis of the attenuation of PEDV

年份：2023

64KIF5B-mediated internalization of FMDV promotes virus infection

作者： Zhang, Wei; Yang, Fan; Yang, Yang; Cao, Weijun; Shao, Wenhua; Wang, Jiali; Huang, Mengyao; Chen, Zhitong; Zhao, Xiaoyi; Li, Weiwei; Zhu, Zixiang; Zheng, Haixue; Zhang, Wei; Yang, Fan; Yang, Yang; Cao, Weijun; Shao, Wenhua; Wang, Jiali; Huang, Mengyao; Chen, Zhitong; Zhao, Xiaoyi; Li, Weiwei; Zhu, Zixiang; Zheng, Haixue; SCI

机构： Lanzhou Univ, Lanzhou Vet Res Inst, State Key Lab Anim Dis Control & Prevent, Chinese Acad Agr Sci,Coll Vet Med, Lanzhou 730000, Peoples R China; Gansu Prov Res Ctr Basic Disciplines Pathogen Biol, Lanzhou 730046, Peoples R China;

来源：VIROLOGICA SINICA

关键词： FMDV; VP1 protein; KIF5B; Endosome; Clathrin

年份：2024

65The multiple roles of viral 3D^pol protein in picornavirus infections

作者： Nie, Zhenyu; Zhai, Fengge; Zhang, Han; Zheng, Haixue; Pei, Jingjing; Nie, Zhenyu; Zhai, Fengge; Zhang, Han; Zheng, Haixue; Pei, Jingjing; Zhai, Fengge; Zheng, Haixue; SCI

机构： Lanzhou Univ, Lanzhou Vet Res Inst, Chinese Acad Agr Sci, Coll Vet Med,State Key Lab Anim Dis Control & Prev, Lanzhou, Peoples R China; Gansu Prov Res Ctr Basic Disciplines Pathogen Biol, Lanzhou, Peoples R China; Henan Agr Univ, Coll Vet Med, Zhengzhou, Peoples R China;

来源：VIRULENCE

关键词： Picornaviruses; 3D(pol); RNA-dependent RNA polymerase; virus-host interaction; RdRp inhibitor

年份：2024

66Quantum dot fluorescent microsphere-based immunochromatographic strip for detecting PRRSV antibodies

作者： Yang, Rui; Zhang, Yong; Zhao, Xingxu; Yang, Rui; Ru, Yi; Hao, Rongzeng; Li, Yajun; Zheng, Haixue; Yang, Rui; Wang, Huibao; Zhang, Tao; SCI

机构： Gansu Agr Univ, Coll Vet Med, Lanzhou 730070, Gansu, Peoples R China; Lanzhou Univ, Chinese Acad Agr Sci, Lanzhou Vet Res Inst, State Key Lab Anim Dis Control & Prevent,Coll Vet, Lanzhou 730000, Gansu, Peoples R China; China Agr Veterinarian Biol Sci & Technol Co Ltd, Lanzhou 730046, Gansu, Peoples R China; Gansu Forestry Technol Coll, Coll Modern Agr Engn, Tianshui 741020, Gansu, Peoples R China;

来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

关键词： Porcine reproductive and respiratory syndrome; Quantum dot fluorescent microsphere; Immunochromatography strip; Monoclonal antibody

年份：2024

67The Development of a Highly Potent and Selective Human Toll-like Receptor 2 Agonist: Synthesis and Biological Evaluation of CaLGL-1 and Its Derivatives

作者： Jia, Hongbin; Luo, Zhikuan; Jing, Ruijun; Yao, Bowen; Lv, Tinghong; Wang, Xiaolei; Jia, Hongbin; Luo, Zhikuan; Jing, Ruijun; Yao, Bowen; Lv, Tinghong; Wang, Xiaolei; Luo, Zhikuan; Zheng, Haixue; Wang, Xiaolei; Zheng, Haixue; SCI

机构： Lanzhou Univ, Dept Chem, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China; Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China; Lanzhou Univ, Lanzhou Vet Res Inst, Chinese Acad Agr Sci, Coll Vet Med,State Key Lab Anim Dis Control & Prev, ,PR, Lanzhou 730000, Peoples R China; Gansu Prov Res Ctr Basic Disciplines Biol, Lanzhou 730000, Peoples R China;

来源：JOURNAL OF MEDICINAL CHEMISTRY

年份：2024

68Plasminogen activator urokinase interacts with the fusion protein and antagonizes the growth of Peste des petits ruminants virus

作者： Wu, Junhuang; Yang, Wenping; Wu, Jingyan; He, Jijun; Ru, Yi; Ren, Jingjing; Zheng, Haixue; Shang, Youjun; Li, Dan; Wu, Junhuang; Yang, Wenping; Wu, Jingyan; He, Jijun; Ru, Yi; Ren, Jingjing; Zheng, Haixue; Shang, Youjun; Li, Dan; Li, Lingxia; Wang, Yong; SCI

机构： Lanzhou Univ, Lanzhou Vet Res Inst, State Key Lab Anim Dis Control & Prevent, Chinese Acad Agr Sci,Coll Vet Med, Lanzhou, Peoples R China; Gansu Prov Res Ctr Basic Disciplines Pathogen Biol, Lanzhou, Peoples R China; Qinghai Univ, Coll Agr & Anim Husb, Xining, Peoples R China; Anhui Agr Univ, Coll Anim Sci & Technol, Hefei, Peoples R China;

来源：JOURNAL OF VIROLOGY

关键词： Peste des petits ruminants virus; fusion protein; plasminogen activator urokinase; VISA

年份：2024

69Identification and verification of the role of key metabolites and metabolic pathways on ASFV replication

作者： Shi, Zunji; Yang, Xing; Shi, Xijuan; Zhang, Dajun; Zhao, Dengshuai; Hao, Yu; Yang, Jinke; Bie, Xintian; Yan, Wenqian; Chen, Guohui; Chen, Lingling; Liu, Xiangtao; Zheng, Haixue; Zhang, Keshan; Shi, Zunji; Zhang, Keshan; Zhang, Keshan; SCI

机构： Lanzhou Univ, Chinese Acad Agr Sci, Coll Vet Med, Lanzhou Vet Res Inst,State Key Lab Anim Dis Contro, Lanzhou 730000, Peoples R China; Lanzhou Univ, Coll Pastoral Agr Sci & Technol, Ctr Grassland Microbiome, State Key Lab Herbage Improvement & Grassland Agro, Lanzhou 730000, Peoples R China; Chinese Acad Agr Sci, Lanzhou Vet Res Inst, 1 Xujiaping, Lanzhou 730046, Peoples R China;

来源：ISCIENCE

年份：2024

70A genome-wide CRISPR screening uncovers that TOB1 acts as a key host factor for FMDV infection via both IFN and EGFR mediated pathways

作者： Peng, Gaochuang; Liu, Tianran; Wang, Yuzhe; Du, Xuguang; Hu, Siyu; Wu, Sen; Zhao, Yaofeng; Peng, Gaochuang; Liu, Tianran; Qi, Xiaolan; Ren, Jingjing; Peng, Jiangling; Li, Dan; Zheng, Haixue; SCI

机构： China Agr Univ, Coll Biol Sci, Frontiers Sci Ctr Mol Design Breeding, State Key Lab Anim Biotech Breeding,Natl Engn Lab, Beijing, Peoples R China; Lanzhou Univ, Lanzhou Vet Res Inst, State Key Lab Anim Dis Control & Prevent, Chinese Acad Agr Sci,Coll Vet Med, Lanzhou, Peoples R China;

来源：PLOS PATHOGENS

年份：2024