Antiviral Activities of Carbazole Derivatives against Porcine Epidemic Diarrhea Virus In Vitro

Chen, Zheng; Chen, Jinfeng; Wei, Xiaodong; Hua, Huiying; Zhang, Jinhua; Song, Deping; Ye, Yu; Tang, Yuxin; Ding, Zhen; Chen, Zheng; Chen, Jinfeng; Zhang, Jinhua; Song, Deping; Ye, Yu; Tang, Yuxin; Ding, Zhen; Hu, Ruiming; Ding, Nengshui; Ke, Shaoyong; SCI

机构： Jiangxi Agr Univ, Coll Anim Sci & Technol, Dept Vet Prevent Med, Nanchang 330045, Jiangxi, Peoples R China; Jiangxi Agr Univ, Coll Anim Sci & Technol, Jiangxi Engn Res Ctr Anim Hlth Prod, Nanchang 330045, Jiangxi, Peoples R China; Jiangxi Agr Univ, Inst Anim Populat Hlth, Coll Anim Sci & Technol, Jiangxi Prov Key Lab Anim Hlth, Nanchang 330045, Jiangxi, Peoples R China; Jiangxi Agr Univ, State Key Lab Pig Genet Improvement & Prod Techno, Nanchang 330045, Jiangxi, Peoples R China; Hubei Acad Agr Sci, Hubei Biopesticide Engn Res Ctr, Wuhan 430064, Peoples R China;

关键词： antiviral drug; carbazole derivatives; porcine epidemic diarrhea virus

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2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales

Kuhn, Jens H.; Wada, Jiro; Adkins, Scott; Al Kubrusli, Rim; Buettner, Carmen; Gaskin, Thomas; Huettner, Florian; von Bargen, Susanne; Alkhovsky, Sergey V.; Amarasinghe, Gaya K.; Avsic-Zupanc, Tatjana; Ayllon, Maria A.; Bahl, Justin; Balkema-Buschmann, Anne; Ballinger, Matthew J.; Basler, Christopher F.; Bavari, Sina; Beer, Martin; Rubbenstroth, Dennis; Bejerman, Nicolas; Bennett, Andrew J.; Bente, Dennis A.; Bergeron, Eric; Bird, Brian H.; Blair, Carol D.; Blasdell, Kim R.; Blystad, Dag-Ragnar; Bojko, Jamie; Borth, Wayne B.; Hu, John S.; Kawate, Michael; Olmedo-Velarde, Alejandro; Park, Adam C.; Sugano, Jari; Uchida, Janice; Bradfute, Steven; Breyta, Rachel; Briese, Thomas; Briese, Thomas; Brown, Paul A.; Brown, Judith K.; Buchholz, Ursula J.; Buchmeier, Michael J.; Bukreyev, Alexander; Burt, Felicity; Burt, Felicity; Calisher, Charles H.; Cao, Mengji; Zhang, Song; Casas, Inmaculada; Chandran, Kartik; Charrel, Remi N.; de Lamballerie, Xavier; Cheng, Qi; Hu, Tao; Wang, Yaqin; Wu, Jiangxiang; Chiaki, Yuya; Chiapello, Marco; Ciuffo, Marina; Peracchio, Carlotta; Vaira, Anna Maria; Vallino, Marta; Choi, Il-Ryong; Choi, Il-Ryong; Crozier, Ian; Dal Bo, Elena; de la Torre, Juan Carlos; de Swart, Rik L.; Debat, Humberto; Dheilly, Nolwenn M.; Di Cicco, Emiliano; Di Paola, Nicholas; Dye, John M.; Garrison, Aura R.; Palacios, Gustavo; Di Serio, Francesco; Rubino, Luisa; Dietzgen, Ralf G.; Digiaro, Michele; Dolnik, Olga; Drebot, Michael A.; Drexler, J. Felix; Junglen, Sandra; Marklewitz, Marco; Paraskevopoulou, Sofia; Drexler, J. Felix; Junglen, Sandra; Marklewitz, Marco; Paraskevopoulou, Sofia; Drexler, J. Felix; Junglen, Sandra; Marklewitz, Marco; Paraskevopoulou, Sofia; Dundon, William G.; Duprex, W. Paul; Durrwald, Ralf; Easton, Andrew J.; Ebihara, Hideki; Elbeaino, Toufic; Ergunay, Koray; Fooks, Anthony R.; Forgia, Marco; Formenty, Pierre B. H.; Koloniuk, Igor; Freitas-Astua, Juliana; Fu, Jingjing; Han, Tong; Yang, Caixia; Fuerl, Stephanie; Gago-Zachert, Selma; Garcia, Maria Laura; Garcia-Sastre, Adolfo; Gaskin, Thomas; Gonzalez, Jean-Paul J.; Griffiths, Anthony; Muehlberger, Elke; Griffiths, Anthony; Muehlberger, Elke; Goldberg, Tony L.; Groschup, Martin H.; Guenther, Stephan; Hall, Roy A.; Hammond, John; Hepojoki, Jussi; Hewson, Roger; Hong, Jiang; Hong, Ni; Li, Longhui; Liu, Huazhen; Wang, Guoping; Wang, Yanxiang; Wen, Shaohua; Yang, Zuokun; Zhang, Zhe; Horie, Masayuki; Hughes, Holly R.; Lambert, Amy J.; Hyndman, Timothy H.; Ilyas, M.; Jalkanen, Risto; Jiang, Daohong; Jiang, Daohong; Junglen, Sandra; Marklewitz, Marco; Paraskevopoulou, Sofia; Kadono, Fujio; Tsuda, Shinya; Kaukinen, Karia H.; Li, Shaorong; Miller, Kristina M.; Tabata, Amy; Klempa, Boris; Klingstrom, Jonas; Kondo, Hideki; Koonin, Eugene V.; Wolf, Yuri I.; Krupovic, Mart; Kubota, Kenji; Usugi, Tomio; Kurath, Gael; Laenen, Lies; Maes, Pie; Langevin, Stanley L.; Lee, Benhur; Lefkowitz, Elliot J.; Leroy, Eric M.; Li, Jianrong; Lukashevich, Igor S.; Lukashevich, Igor S.; de Souza, William Marciel; Marshall, Sergio H.; Marzano, Shin-Yi L.; Massart, Sebastien; McCauley, John W.; Melzer, Michael; Mielke-Ehret, Nicole; Muehlbach, Hans-Peter; Ming, Tobi J.; Mirazimi, Ali; Mordecai, Gideon J.; Naidu, Rayapati; Natsuaki, Tomohide; Navarro, Jose A.; Netesov, Sergey V.; Neumann, Gabriele; Nowotny, Norbert; Pallas, Vicente; Palyi, Bernadett; Papa, Anna; Parrish, Colin R.; Patterson, David A.; Pauvolid-Correa, Alex; Pauvolid-Correa, Alex; Paweska, Janusz T.; Payne, Susan; Perez, Daniel R.; Postler, Thomas S.; Qi, Liying; Xu, Lei; Radoshitzky, Sheli R.; Resende, Renato O.; Reyes, Carina A.; Luna, Gabriel Robles; Rima, Bertus K.; Romanowski, Victor; Runstadler, Jonathan A.; Sabanadzovic, Sead; Salvato, Maria S.; Sang, Rosemary; Tchouassi, David P.; Torto, Baldwyn; Sasaya, Takahide; Schulze, Angela D.; Schwemmle, Martin; Shi, Mang; Shi, Xiaohong; Shi, Zhengli; Shimomoto, Yoshifumi; Shirako, Yukio; Siddell, Stuart G.; Simmonds, Peter; Sironi, Manuela; Smagghe, Guy; Smither, Sophie; Song, Jin-Won; Spann, Kirsten; Spengler, Jessica R.; Stenglein, Mark D.; Stone, David M.; Suttle, Curtis A.; Suttle, Curtis A.; Suttle, Curtis A.; Suttle, Curtis A.; Suttle, Curtis A.; Takada, Ayato; Takeuchi, Shigeharu; Teffer, Amy; Tesh, Robert B.; Vasilakis, Nikos; Thornburg, Natalie J.; Tomitaka, Yasuhiro; Tomonaga, Keizo; Tordo, Noel; Towner, Jonathan S.; Tu, Changchun; Turina, Massimo; Tzanetakis, Ioannis E.; van den Hoogen, Bernadette; Varsani, Arvind; Verbeek, Martin; Wahl, Victoria; Walker, Peter J.; Wang, Lin-Fa; Waqas, Muhammad; Wei, Taiyun; Whitfield, Anna E.; Williams, John V.; Yanagisawa, Hironobu; Zerbini, F. Murilo; Zhai, Lifeng; Zhang, Jinguo; Zhou, Xueping; Towner, Jonathan S.; Ayllon, Maria A.; Bojko, Jamie; Breyta, Rachel; Debat, Humberto; Gonzalez, Jean-Paul J.; Hepojoki, Jussi; Horie, Masayuki; Junglen, Sandra; Laenen, Lies; Marklewitz, Marco; Nowotny, Norbert; Park, Adam C.; Pauvolid-Correa, Alex; Varsani, Arvind; Agwanda, Bernard R.; Agwanda, Bernard R.; Ferguson, Hugh W.; Franova, Jana; Gao, George Fu; Hongo, Seiji; Kobinger, Gary; Nunes, Marcio R. T.; Rota, Paul; Sall, Amadou Alpha; Zhang, Yong-Zhen; Zhang, Yong-Zhen; Zhang, Yong-Zhen; SCI

机构： NIAID, Integrated Res Facil Ft Detrick, NIH, Frederick, MD 21702 USA; ARS, USDA, US Hort Res Lab, Ft Pierce, FL USA; Humboldt Univ, Div Phytomed, Fac Life Sci, Berlin, Germany; Minist Hlth Russian Federat, DI Ivanovsky Inst Virol NF Gamaleya, Natl Ctr Epidemiol & Microbiol, Moscow, Russia; Washington Univ, Sch Med, Dept Pathol & Immunol, St Louis, MO 63110 USA; Univ Ljubljana, Fac Med, Ljubljana, Slovenia; Univ Politecn Madrid, Inst Nacl Invest & Tecnol Agr & Alimentaria, Ctr Biotecnol & Genom Plantas, Campus Montegancedo, Madrid, Spain; Univ Georgia, Dept Infect Dis, Inst Bioinformat, Ctr Ecol Infect Dis,Dept Epidemiol & Biostat, Athens, GA 30602 USA; Friedrich Loeffler Inst, Inst Novel & Emerging Infect Dis, Fed Res Inst Anim Hlth, Greifswald, Germany; Mississippi State Univ, Dept Biol Sci, Mississippi State, MS 39762 USA; Georgia State Univ, Inst Biomed Sci, Ctr Microbial Pathogenesis, Atlanta, GA 30303 USA; Edge BioInnovat Consulting & Mgt, Frederick, MD USA; Friedrich Loeffler Inst, Inst Diagnost Virol, Greifswald, Germany; Consejo Nacl Invest Cient & Tecn, INTA, UFyMA, Cordoba, Argentina; Naval Med Res Ctr Frederick, Genom & Bioinformat Dept, Biol Def Res Directorate, Frederick, MD USA; Univ Texas Med Branch, Galveston, TX 77555 USA; Ctr Dis Control & Prevent, Viral Special Pathogens Branch, Div High Consequence Pathogens & Pathol, Atlanta, GA USA; Univ Calif Davis, Sch Vet Med, One Hlth Inst, Davis, CA 95616 USA; Colorado State Univ, Dept Microbiol Immunol & Pathol, Ft Collins, CO 80523 USA; Commonwealth Sci & Ind Res Org CSIRO, Australian Ctr Dis Preparedness, Geelong, Vic, Australia; NIBIO Norwegian Inst Bioecon Res, Oslo, Norway; Univ Teesside, Sch Hlth & Life Sci, Middlesbrough TS1 3BX, Cleveland, England; Univ Hawaii, Honolulu, HI USA; Univ New Mexico, Hlth Sci Ctr, Albuquerque, NM 87131 USA; Univ Washington, Seattle, WA 98195 USA; Columbia Univ, Mailman Sch Publ Hlth, Ctr Infect & Immun, New York, NY USA; Columbia Univ, Mailman Sch Publ Hlth, Dept Epidemiol, New York, NY USA; French Agcy Food Environm & Occupat Heath Safety, Lab Ploufragan Plouzane Niort, Ploufragan, France; Univ Arizona, Sch Plant Sci, Tucson, AZ USA; NIAID, RNA Viruses Sect, Infect Dis Lab, NIH, 9000 Rockville Pike, Bethesda, MD 20892 USA; Univ Calif Irvine, Dept Mol Biol & Biochem, Irvine, CA 92717 USA; Univ Texas Med Branch, Galveston Natl Lab, Galveston, TX 77555 USA; Univ Free State, Div Virol, Natl Hlth Lab Serv, Bloemfontein, South Africa; Univ Free State, Div Virol, Bloemfontein, South Africa; Colorado State Univ, Ft Collins, CO 80523 USA; Southwest Univ, Citrus Res Inst, Natl Citrus Engn & Technol Res Ctr, Chongqing, Peoples R China; Inst Salud Carlos III, Resp Virus & Influenza Unit, Natl Microbiol Ctr, Madrid, Spain; Albert Einstein Coll Med, Dept Microbiol & Immunol, Bronx, NY 10467 USA; Aix Marseille Univ, Unite Virus Emergents, IHU Mediterranee Infect, Inserm 1207,IRD 190, Marseille, France; Zhejiang Univ, Inst Biotechnol, State Key Lab Rice Biol, Hangzhou, Peoples R China; NARO, Inst Fruit Tree & Tea Sci, Grape & Persimmon Res Stn, Higashihiroshima, Hiroshima, Japan; Natl Res Council Italy CNR, Inst Sustainable Plant Protect, Str Cacce 73, I-10135 Turin, Italy; Plant Breeding Genet & Biotechnol Div, Los Banos, Philippines; Int Rice Res Inst, Los Banos, Philippines; Frederick Natl Lab Canc Res, Clin Monitoring Res Program Directorate, Frederick, MD USA; Univ La Plata, CIDEFI, Fac Ciencias Agr & Forest, La Plata, Argentina; Scripps Res Inst, Dept Immunol & Microbiol IMM 6, La Jolla, CA 92037 USA; Erasmus MC, Univ Med Ctr Rotterdam, Dept Virosci, Rotterdam, Netherlands; Inst Nacl Tecnol Agr IPAVE CIAP INTA, Ctr Invest Agr, Cordoba, Argentina; ANSES Anim Hlth Lab, ENVA, INRAE, UMR 1161 Virol ANSES, F-94704 Maisons Alfort, France; Pacific Salmon Fdn, Vancouver, BC, Canada; US Army, Med Res Inst Infect Dis, Frederick, MD USA; CNR, Ist Protez Sostenibile Piante, Bari, Italy; Univ Queensland, Queensland Alliance Agr & Food Innovat, St Lucia, Qld, Australia; Ist Agron Mediterraneo Bari, CIHEAM, Valenzano, Italy; Philipps Univ Marburg, Inst Virol, Marburg, Germany; Publ Hlth Agcy Canada, Natl Microbiol Lab, Zoonot Dis & Special Pathogens, Winnipeg, MB, Canada; Charite Univ Med Berlin, Inst Virol, Berlin, Germany; Free Univ Berlin, Berlin, Germany; Humboldt Univ, Berlin, Germany; IAEA, Joint FAO IAEA Div Nucl Tech Food & Agr, Dept Nucl Sci & Applicat, Anim Prod & Hlth Lab, Vienna, Austria; Univ Pittsburgh, Sch Med, Pittsburgh, PA USA; Robert Koch Inst, Berlin, Germany; Univ Warwick, Sch Life Sci, Coventry, W Midlands, England; Mayo Clin, Dept Mol Med, Rochester, MN USA; Ist Agron Mediterraneo Bari, Valenzano, Italy; Hacettepe Univ, Dept Med Microbiol, Virol Unit, Fac Med, Ankara, Turkey; Anim & Plant Hlth Agcy, Weybridge, Surrey, England; CNR, Inst Sustainable Plant Protect, Turin, Italy; WHO, Geneva, Switzerland; CAS, Inst Plant Mol Biol, Plant Virol Dept, Biol Ctr, Ceske Budejovice, Czech Republic; Embrapa Cassava & Fruits, Cruz Das Almas, BA, Brazil; Shenyang Univ, Coll Life Sci & Engn, Shenyang, Liaoning, Peoples R China; Humboldt Univ, Div Phytomed, Albrecht Daniel Thaer Inst Crop & Anim Sci, Berlin, Germany; Martin Luther Univ Halle Wittenberg, Inst Biochem & Biotechnol, Halle, Germany; CONICET UNLP, Fac Ciencias Exactas, Nstituto Biotecnol & Biol Mol, La Plata, Argentina; Icahn Sch Med Mt Sinai, New York, NY 10029 USA; Landesamt Iandliche Entwicklung, Landwirtschaft & Flurneuordnung, Frankfurt, Oder, Germany; Georgetown Univ, Sch Med, Dept Microbiol & Immunol, Div Biomed Grad Res Org, Washington, DC 20057 USA; Boston Univ, Sch Med, Dept Microbiol, Boston, MA 02215 USA; Boston Univ, Sch Med, Natl Emerging Infect Dis Labs, Boston, MA 02215 USA; Univ Wisconsin, Sch Vet Med, Dept Pathobiol Sci, Madison, WI 53706 USA; Friedr h Loeffler Inst, Inst Novel & Emerging Infect Dis, Greifswald, Germany; Bernhard Nocht Inst Trop Med, Dept Virol, WHO Collaborating Ctr Arboviruses & Hemorrhag Fev, Hamburg, Germany; Univ Queensland, Australian Infect Dis Res Ctr, Sch Chem & Mol Biosci, Brisbane, Qld, Australia; ARS, Floral & Nursery Plants Res Unit, USDA, USNA, Beltsville, MD USA; Univ Helsinki, Dept Virol, Medicum, Helsinki, Finland; London Sch Hygeine & Trop Med, London, England; Zhejiang Univ, Anal Ctr Agrobiol & Environm Sci, Hangzhou, Peoples R China; Huazhong Agr Univ, Coll Plant Sci & Technol, Key Lab Plant Pathol Hubei Prov, Wuhan, Peoples R China; Kyoto Univ, Hakubi Ctr Adv Res, Kyoto, Japan; Ctr Dis Control & Prevent, Ft Collins, CO USA; Murdoch Univ, Sch Vet Med, Murdoch, WA, Australia; North Carolina State Univ, Entomol & Plant Pathol, Raleigh, NC USA; Silva Lappon, Rovaniemi, Finland; Huazhong Agr Univ, State Key Lab Agr Microbiol, Wuhan, Hubei, Peoples R China; Rice Res Inst, Rice Breeding Innovat Platform, Los Banos, Laguna, Philippines; Berlin Inst Hlth, Berlin, Germany; Hosei Univ, Fac Biosci & Appl Chem, Dept Clin Plant Sci, Koganei, Tokyo, Japan; Fisheries & Oceans Canada, Pacific Biol Stn, 3190 Hammond Bay Rd, Nanaimo, BC V9T 6N7, Canada; Slovak Acad Sci, Inst Virol, Biomed Res Ctr, Bratislava, Slovakia; Karolinska Univ Hosp, Karolinska Inst, Dept Med Huddinge, Ctr Infect Med, Stockholm, Sweden; Okayama Univ, Inst Plant Sci & Resources, Kurashiki, Okayama, Japan; NIH, Natl Ctr Biotechnol Informat, Natl Lib Med, Bldg 10, Bethesda, MD 20892 USA; Inst Pasteur, Archaeal Virol Unit, Paris, France; NARO, Cent Reg Agr Res Ctr, Tsukuba, Ibaraki, Japan; US Geol Survey, Western Fisheries Res Ctr, Seattle, WA USA; Katholieke Univ Leuven, Rega Inst, Zoonot Infect Dis Unit, Leuven, Belgium; Univ Washington, Dept Microbiol, Washington, DC USA; Icahn Sch Med Mt Sinai, Dept Microbiol, New York, NY 10029 USA; Univ Alabama Birmingham, Birmingham, AL USA; Montpellier Univ Unit, French Natl Res Inst Sustainable Dev IRD, CNRS, MIVEGEC,IRD, Montpellier, France; Ohio State Univ, Coll Vet Med, Dept Vet Biosci, Columbus, OH 43210 USA; Univ Louisville, Sch Med, Dept Pharmacol & Toxicol, Louisville, KY 40292 USA; Univ Louisville, Ctr Predict Med Biodefense & Emerging Infect Dis, Louisville, KY 40292 USA; Univ Sao Paulo, Virol Res Ctr, Ribeirao Preto, Brazil; Pontificia Univ Catolica Valparaiso, Campus Curauma, Valparaiso, Chile; ARS, USDA, Washington, DC USA; Univ Liege, Plant Pathol Lab, Gembloux Agrobio Tech, TERRA, Liege, Belgium; Francis Crick Inst, Worldwide Influenza Ctr, London, England; 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Wageningen Univ & Res Biointeract & Plant Hlth, Wageningen, Netherlands; Natl Biodefense Anal & Countermeasures Ctr, Frederick, MD USA; Univ Queensland, Sch Chem & Mol Biosci, St Lucia, Qld, Australia; Duke NUS Med Sch, Programme Emerging Infect Dis, Singapore, Singapore; Huazhong Agr Univ, Coll Plant Sci & Technol, Key Lab Crop Dis Monitoring & Safety Control Hube, Wuhan, Hubei, Peoples R China; Fujian Agr & Forestry Univ, Inst Plant Virol, Fujian Prov Key Lab Plant Virol, Fuzhou, Fujian, Peoples R China; North Carolina State Univ, Dept Entomol & Plant Pathol, Raleigh, NC USA; Yokohama Plant Protect Stn, Narita Branch, Chiba, Japan; Univ Fed Vicosa, Inst Biotecnol Aplicada Agr, Dept Fitopatol, Vicosa, MG, Brazil; Minist Educ, Key Lab Hort Plant Biol, Wuhan 430070, Hubei, Peoples R China; Hubei Acad Agr Sci, Res Inst Fruit & Tea, Natl Sand Pear Germplasm Repository Wuchang, Wuhan, Hubei, Peoples R China; Chinese Acad Agr Sci, Inst Plant Protect, State Key Lab Biol Plant Dis & Insect Pests, Beijing, Peoples R China; Inst Pasteur Guinee, Conakry, Guinea; Univ Politecn Madrid, Dept Biotecnol Biol Vegetal, Escuela Tecn Super Ingn Agron Alimentaria & Biosi, Madrid, Spain; Univ Teesside, Natl Horizons Ctr, Darlington DL1 1HG, Durham, England; Consejo Nacl Invest Cient & Tecn UFYMA CONICET, Unidad Fitopatol & Modelizac Agr, Cordoba, Argentina; CTP, Centaurus Biotechnol, Manassas, VA USA; Univ Zurich, Inst Vet Pathol, Vetsuisse Fac, Zurich, Switzerland; Osaka Prefecture Univ, Grad Sch Life & Environm Sci, Div Vet Sci, Izumisano, Japan; German Ctr Infect Res, Berlin, Germany; Univ Hosp Leuven, Dept Lab Med, Leuven, Belgium; German Ctr Infect Res DZIF, Berlin, Germany; Mohammed Bin Rashid Univ Med & Hlth Sci, Coll Med, Dubai, U Arab Emirates; Hawaii Dept Agr, Honolulu, HI USA; Fiocruz MS, Lab Resp Viruses & Measles, Rio De Janeiro, Brazil; Univ Cape Town, Dept Clin Lab Sci, Struct Biol Res Unit, Cape Town, South Africa; Natl Museums Kenya, Zool Dept, Nairobi, Kenya; Jomo Kenyatta Univ Agr & Technol, Nairobi, Kenya; St Georges Univ, Sch Vet Med, True Blue, Grenada; Chinese Ctr Dis Control & Prevent, Natl Inst Viral Dis Control & Prevent, Beijing, Peoples R China; Yamagata Univ, Dept Infect Dis, Fac Med, Yamagata, Japan; Univ Laval, Dept Microbiol Immunol & Infect Dis, Quebec City, PQ, Canada; Minist Hlth, Evandro Chagas Inst, Belem, Para, Brazil; Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Atlanta, GA USA; Inst Pasteur, Dakar, Senegal; Chinese Ctr Dis Control & Prevent, Natl Inst Communicable Dis Control & Prevent, Beijing, Peoples R China; Fudan Univ, Shanghai Publ Hlth Clin Ctr, Shanghai, Peoples R China; Fudan Univ, Inst Biomed Sci, Shanghai, Peoples R China;

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The key regulator LcERF056 enhances salt tolerance by modulating reactive oxygen species-related genes in Lotus corniculatus

Wang, Dan; Sun, Zhanmin; Tang, Yixiong; Wu, Yanmin; Wang, Dan; Hu, Xinxu; Xiong, Junbo; Hu, Lizhen; Xu, Yuandong; Hu, Xinxu; SCI

机构： Chinese Acad Agr Sci, Biotechnol Res Inst, Beijing, Peoples R China; China West Normal Univ, Minist Educ, Key Lab Southwest China Wildlife Resources Conser, Nanchong, Peoples R China; Hunan Agr Univ, Coll Anim Sci & Technol, Changsha, Peoples R China; Hubei Acad Agr Sci, Inst Anim & Vet Sci, Hubei Key Lab Anim Embryo & Mol Breeding, Wuhan, Peoples R China; Jiangxi Acad Agr Sci, Inst Anim & Vet Sci, Nanchang, Jiangxi, Peoples R China; ChongQing Acad Anim Sci, Chongqing, Peoples R China; Huanshan Grp, Qingdao, Peoples R China;

关键词： ERF transcription factor; Salt stress; Regulation mechanism; Lotus corniculatus

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Overexpression of ?-cyanoalanine synthase of Prunus persica increases salt tolerance by modulating ROS metabolism and ion homeostasis

Shen, Wanqi; Liu, Dan; Zhang, He; Zhu, Wei; Li, Guohuai; Liu, Junwei; Zhang, He; Zhu, Wei; He, Hanzi; SCI

机构： Huazhong Agr Univ, Coll Hort & Forest Sci, Key Lab Hort Plant Biol, Minist Educ, Wuhan 430070, Hubei, Peoples R China; Chinese Acad Trop Agr Sci, Haikou Expt Stn, Haikou 570102, Hainan, Peoples R China; Hubei Acad Agr Sci, Inst Fruit & Tea, Wuhan 430064, Hubei, Peoples R China; Huazhong Agr Univ, Coll Plant Sci & Technol, Wuhan 430070, Hubei, Peoples R China;

关键词： ?-cyanoalanine synthase; Ion homeostasis; Prunus persica; Reactive oxygen species; Salt stress tolerance

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Foliar applied 24-epibrassinolide alleviates salt stress in rice (Oryza sativa L.) by suppression of ABA levels and upregulation of secondary metabolites

Shahzad, Raheel; Shahzad, Raheel; Ewas, Mohamed; Khan, Shahid Ullah; Nishawy, Elsayed; Khan, Amir Hamid; Harlina, Putri Widyanti; Ewas, Mohamed; Nishawy, Elsayed; Zhenyuan, Pan; Nie, Xinhui; Gallego, Pedro P.; Jia, Haitao; SCI

机构： Univ Muhammadiyah Bandung, Fac Sci & Technol, Dept Biotechnol, Bandung, West Java, Indonesia; Huazhong Agr Univ, Natl Key Lab Crop Genet Improvement, Wuhan, Peoples R China; Univ Padjadjaran, Fac Agroind Technol, Dept Food Technol, Bandung, Indonesia; Desert Res Ctr, Dept Plant Genet Resources, Cairo, Egypt; Shihezi Univ, Agr Coll, Key Lab Oasis Ecol Agr Xinjiang Bingtuan, Shihezi, Xinjiang, Peoples R China; Univ Vigo, Dept Plant Biol & Soil Sci, Agrobiotech Hlth, Vigo, Spain; Hubei Acad Agr Sci, Food Crops Inst, Hubei Key Lab Food Crop Germplasm & Genet Improve, Wuhan, Peoples R China;

关键词： 24-Epibrassinolide; rice plant; salt tolerance; secondary metabolism; phenolic compounds; flavonoids

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Do Strigolactones Regulate Bud Winter Dormancy and Charactrisitc Secondary Metabolism in Tea?

Feng, Lin; Gong, Ziming; Liu, Yanli; Liu, Guofeng; SCI

机构： Hubei Acad Agr Sci, Hubei Tea Engn & Technol Res Ctr, Inst Fruit & Tea, Wuhan 430064, Peoples R China; Xinyang Normal Univ, Coll Life Sci, Xinyang 464000, Peoples R China;

关键词： Camellia sinensis; strigolactones; winter dormancy; secondary metabolites

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Cost-Effective Production of ATP and S-Adenosylmethionine Using Engineered Multidomain Scaffold Proteins

Yan, Guangbo; Li, Xia; Yang, Jun; Li, Zhongchen; Hou, Jia; Ma, Lixin; Wang, Yaping; Rao, Ben; Hu, Yong; SCI

机构： Hubei Univ, Fac Biol, Hubei Key Lab Ind Biotechnol, State Key Lab Biocatalysis & Enzyme,Engn Hubei Co, Wuhan 430062, Peoples R China; Hubei Acad Agr Sci, Biopesticide Branch Hubei Innovat Ctr Agr Sci & T, Natl Biopesticide Engn Technol Res Ctr, Hubei Biopesticide Engn Res Ctr, Wuhan 430064, Peoples R China; Hubei Univ Technol, Hubei Res Ctr Food Fermentat Engn & Technol, Natl Ctr Cellular Regulat & Mol Pharmaceut 111, Key Lab Fermentat Engn,Minist Educ,Hubei Key Lab, Wuhan 430062, Peoples R China;

关键词： S-adenosylmethionine; ATP synthesis; scaffold protein; multi-enzyme cascade

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A systems genetics approach reveals PbrNSC as a regulator of lignin and cellulose biosynthesis in stone cells of pear fruit

Wang, Runze; Xue, Yongsong; Qin, Mengfan; Zhang, Mingyue; Li, Xiaolong; Li, Jiaming; Sun, Manyi; Song, Bobo; Zhang, Jiaying; Zhao, Kejiao; Wu, Jun; Fan, Jing; Hu, Hongju; Yao, Jia-Long; Lin, Tao; Lian, Qun; Li, Xiaolong; Lin, Tao; Zhang, Mingyue; Xue, Cheng; Chen, Xu; Fei, Zhangjun; Fei, Zhangjun; SCI

机构： Nanjing Agr Univ, Coll Hort, State Key Lab Crop Genet & Germplasm Enhancement, Nanjing 210095, Peoples R China; Hubei Acad Agr Sci, Inst Fruit & Tea, Wuhan 430072, Peoples R China; New Zealand Inst Plant & Food Res Ltd, Auckland 1025, New Zealand; Chinese Acad Agr Sci, Agr Genom Inst Shenzhen, Genome Anal Lab, Minist Agr, Shenzhen 518124, Peoples R China; China Agr Univ, Coll Hort, Beijing 100083, Peoples R China; Shandong Agr Univ, Coll Hort Sci & Engn, State Key Lab Crop Biol, Tai An 271018, Shandong, Peoples R China; Fujian Agr & Forestry Univ, Hort Plant Biol & Metabol Ctr, Haixia Inst Sci & Technol, Fuzhou 350002, Peoples R China; Cornell Univ, Boyce Thompson Inst, Ithaca, NY 14853 USA; USDA ARS, Robert W Holley Ctr Agr & Hlth, Ithaca, NY 14853 USA;

关键词： Pear fruit; Co-expression network; eQTL; Stone cell formation; NAC transcription factor; Transcriptional regulation

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The Effect of Exogenous Melatonin on Milk Somatic Cell Count in Buffalo

Lin Feng; Chen Yuxia; Wang Zichen; Li Ming; Gao Tengyun; Liu Shenhe; Li Zipeng; Ahmad, Muhammad Jamil; SCI

机构： Henan Agr Univ, Coll Anim Sci & Vet Med, Zhengzhou, Peoples R China; Hubei Acad Agr Sci, Inst Anim Sci & Vet Med, Wuhan 430064, Peoples R China; Huazhong Agr Univ, Coll Anim Sci & Technol, Key Lab Agr Anim Genet Breeding & Reprod, Minist Educ, Wuhan, Peoples R China;

关键词： Buffalo; Melatonin; Milk; Somatic cell counts

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Expanding the scope of plant genome engineering with Cas12a orthologs and highly multiplexable editing systems

Zhang, Yingxiao; Malzahn, Aimee A.; Yin, Desuo; Pan, Changtian; Cheng, Yanhao; Le, Ysa; McCoy, Bailey; Franklin, Lidiya; Qi, Yiping; Ren, Qiurong; Tang, Xu; Liu, Shishi; Zhou, Jianping; Wang, Jiaheng; Yuan, Mingzhu; Huang, Lan; Yang, Han; Zhao, Yuxin; Fang, Qing; Zheng, Xuelian; Tian, Li; Zhang, Yong; Yin, Desuo; Cheng, Yanhao; Selengut, Jeremy D.; Mount, Stephen M.; Que, Qiudeng; Qi, Yiping; SCI

机构： Univ Maryland, Dept Plant Sci & Landscape Architecture, College Pk, MD 20742 USA; Univ Elect Sci & Technol China, Ctr Informat Biol, Sch Life Sci & Technol, Dept Biotechnol, Chengdu, Peoples R China; Hubei Acad Agr Sci, Food Crop Inst, Wuhan, Hubei, Peoples R China; Nanjing Agr Univ, Coll Agr, Nanjing, Jiangsu, Peoples R China; Univ Maryland, Ctr Bioinformat & Computat Biol, College Pk, MD 20742 USA; Univ Maryland, Dept Cell Biol & Mol Genet, College Pk, MD 20742 USA; Syngenta, Res Triangle Pk, NC USA; Univ Maryland, Inst Biosci & Biotechnol Res, Rockville, MD USA;

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