Molecular detection and genetic diversity of porcine circovirus type 3 in commercial pig farms in Xinjiang province, China

文献类型： 外文期刊

第一作者： Qiao Mengfan

作者： Qiao Mengfan;Wang Xifeng;Zhang Guowu;Meng Qingling;Qiao Jun;Wang Lixia;Qiao Mengfan;Cai Kuojun;Zhang Jinsheng;Zhang Zaichao;Yu Weiwei;Peng Yelong;Cai Xuepeng

作者机构：

关键词： porcine circovirus type 3; molecular detection; genetic diversity; cap gene; China

期刊名称：JOURNAL OF VETERINARY RESEARCH （ 影响因子：1.744； 五年影响因子：1.838 ）

ISSN： 2450-7393

年卷期： 2019 年 63 卷 4 期

页码：

收录情况： SCI

摘要： Introduction: Porcine circovirus type 3 (PCV3) is a newly discovered porcine circovirus. The molecular characteristics and genetic evolution of PCV3 in Xinjiang province, China still being unclear, the aim of the study was their elucidation. Material and Methods: A total of 393 clinical samples were collected from pigs on commercial farms in nine different regions of Xinjiang and phylogenetic analysis based on full-length Cap genes was performed. Results: The prevalence at farm level was 100%, while in all the tested samples it was 22.39%. Nine PCV3 strains were detected in Xinjiang province and they shared 98.9-99.3% nucleotide and 97.5-100.0% Cap gene amino acid sequence identities with other epidemic strains from China and abroad. Compared with other epidemic strains of PCV3, there were 26 base mutation sites in the Cap gene in the nine Xinjiang strains, resulting in the mutation of amino acids at positions 20, 24, 75, 77, 108, 111 and 206. Phylogenetic analysis showed that these strains can be divided into two different genetic groups, to the first of which five strains affiliated and divided between subgroups 1.1 and 1.2, and to the second of which the other four strains affiliated and similarly divided between subgroups 2.1 and 2.2. Conclusion: PCV3 circulates widely among commercial pig farms in Xinjiang province, China, and displays obvious genetic diversity. The results provide epidemiological information useful for the prevention and control of PCV3 infection in the pig industry.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序