Dimeric 2-(2-phenethyl)chromones from agarwood of Aquilaria filaria

文献类型: 外文期刊

第一作者: Yang, Hong-run

作者: Yang, Hong-run;Liu, Fang-Zheng;Jiang, Bei;Dai, Hao-Fu;Yang, Hong-run;Wang, Pei;Liu, Fang-Zheng;Yuan, Jing-Zhe;Cai, Cai-Hong;Wu, Fei;Mei, Wen-Li;Dai, Hao-Fu;Yang, Hong-run;Wang, Pei;Liu, Fang-Zheng;Yuan, Jing-Zhe;Cai, Cai-Hong;Wu, Fei;Mei, Wen-Li;Dai, Hao-Fu

作者机构:

关键词: Agarwood; Aquilaria filaria; 2-(2-phenethyl)chromone dimers; Anti-inflammatory activity

期刊名称:FITOTERAPIA ( 影响因子:3.4; 五年影响因子:3.3 )

ISSN: 0367-326X

年卷期: 2023 年 165 卷

页码:

收录情况: SCI

摘要: Four new 2-(2-phenethyl)chromone dimers (1-4) were isolated from EtOAc extract of agarwood originating from Aquilaria filaria from Philippines. Their structures were elucidated by spectroscopic analysis (1D and 2D NMR, and HRESIMS) and comparison of the experimental and computed ECD curves. Compounds 1-4 exhibited in-hibition of nitric oxide production in lipopolysaccharide-stimulated RAW264.7 cells with IC50 values in the range from 33.94 to 57.53 mu M.

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