Construction of substituted pyrazolo[4,3-c]quinolines via [5+1] cyclization of pyrazole-arylamines with alcohols/amines in one pot
文献类型： 外文期刊
作者： Tang, Dong 1 ; Mu, Yangxiu 1 ; Iqbal, Zafar 1 ; He, Lili 1 ; Jiang, Rui 1 ; Hou, Jing 1 ; Yang, Zhixiang 1 ; Yang, Minghua 2 ;
作者机构： 1.Ningxia Acad Agr & Forestry Sci, Agr Resource & Environm Inst, Ningxia Ctr Agr Organ Synth, Yinchuan, Ningxia, Peoples R China
2.Lishui Univ, Dept Chem, Lishui 323000, Peoples R China
期刊名称：JOURNAL OF HETEROCYCLIC CHEMISTRY （ 影响因子：2.035； 五年影响因子：1.685 ）
ISSN： 0022-152X
年卷期： 2022 年 59 卷 5 期
页码：
收录情况： SCI
摘要： An efficient protocol has been developed for the synthesis of pyrazolo[4,3-c]quinoline derivatives, by reacting (1H-pyrazol-5-yl)anilines and readily available alcohols/amines. A wide range of substrates with diverse functional groups were smoothly converted to the corresponding products in moderate to good yields, under optimal reaction conditions. Furthermore, the strategy also proceeded well with thiol and amino acid to access pyrazolo[4,3-c]quinoline derivatives.
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