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Preparation process optimization, structural characterization and in vitro digestion stability analysis of Antarctic krill (Euphausia superba) peptides-zinc chelate

文献类型： 外文期刊

作者： Sun, Runan 1 ; Liu, Xiaofang 2 ; Yu, Yuan 2 ; Miao, Junkui 2 ; Leng, Kailiang 2 ; Gao, Hua 1 ;

作者机构： 1.Qingdao Univ, Sch Pharm, Dept Med Chem, 38 Dengzhou Rd, Qingdao 266021, Shandong, Peoples R China

2.Minist Agr & Rural Affairs, Key Lab Sustainable Dev Polar Fishery, Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Inst, 106 Nanjing Rd, Qingdao 266071, Shandong, Peoples R China

3.Pilot Natl Lab Marine Sci & Technol Qingdao, Lab Marine Drugs & Bioprod, Qingdao 266200, Shandong, Peoples R China

关键词： Antarctic krill (Euphausia superba); Peptides-zinc chelate; Structural characterization; Chelate site; Simulated gastrointestinal digestion

期刊名称：FOOD CHEMISTRY （ 影响因子：7.514； 五年影响因子：7.516 ）

ISSN： 0308-8146

年卷期： 2021 年 340 卷

页码：

收录情况： SCI

摘要： In the study, a novel kind of peptides-zinc (AKP-Zn) chelate was obtained using the Antarctic krill (Euphausia superba) peptides (AKP) as raw material, the reaction was carried out with the mass ratio of the AKP to ZnSO4 center dot 7H(2)O of 1:2 at pH 6.0 and 60 degrees C for 10 min. The structure and composition of the AKP, including particle size, Zeta potential, molecular weight distribution, amino acid composition, microstructure and surface elemental composition, changed significantly after chelating with zinc. The result of Fourier transform infrared spectroscopy indicated that zinc could be chelated by carboxyl oxygen and amino nitrogen atoms of the AKP. Furthermore, compared with zinc sulfate and zinc gluconate, the AKP-Zn chelate was more stable at various pH conditions and the simulated gastrointestinal digestion experiment. These findings would provide a scientific basis for developing new zinc supplements and the high-value utilization of Antarctic krill protein resource.

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