Two new 2-(2-phenethyl)chromone derivatives from agarwood of Aquilaria walla and their cytotoxicity
文献类型： 外文期刊
作者： Wang, Yue-Yue 1 ; Wang, Hao 2 ; Mi, Cheng-Neng 2 ; Li, Wei 2 ; Gai, Cui-Juan 2 ; Yuan, Jing-Zhe 2 ; Mei, Wen-Li 2 ; Xu, S 1 ;
作者机构： 1.Hainan Univ, Coll Trop Agr, Haikou 570228, Hainan, Peoples R China
2.Chinese Acad Trop Agr Sci, Hainan Engn Res Ctr Agarwood, Minist Agr, Key Lab Biol & Genet Resources Trop Crops, Haikou 571101, Hainan, Peoples R China
3.Hainan Univ, Coll Hort, Haikou 570228, Hainan, Peoples R China
关键词： Aquilaria walla; Agarwood; Dimeric 2-(2-phenethyl)chromone; Flavonoid-2-(2-phenethyl)chromone; Cytotoxicity
期刊名称：PHYTOCHEMISTRY LETTERS （ 影响因子：1.459； 五年影响因子：1.601 ）
ISSN： 1874-3900
年卷期： 2021 年 42 卷
页码：
收录情况： SCI
摘要： Two new 2-(2-phenethyl)chromone derivatives were isolated from agarwood of Aquilaria walla, including a dimeric 2-(2-phenethyl)chromone (1) and a flavonoid-2-(2-phenethyl)chromone (2). Their structures were established based on spectroscopic methods including HRESIMS, 1D, and 2D NMR. Compounds 1 and 2 showed cytotoxic activity against five human cancer cell lines with IC50 values ranging from 4.96?44.34 ?M.
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