文献类型： 外文期刊
作者： Wang, Yancui 1 ; Wang, Hao 1 ; Mei, Wenli 1 ; Liu, Shoubai 3 ; Kong, Fandong 1 ; Zhao, Youxing 1 ; Dai, Haofu 1 ;
作者机构： 1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Key Lab Biol & Genet Resources Trop Crops, Minist Agr, Haikou 571101, Hainan, Peoples R China
2.Hainan Key Lab Res & Dev Nat Prod Li Folk Med, Haikou 571101, Hainan, Peoples R China
3.Hainan Univ, Inst Trop Agr & Forestry, Haikou, Hainan, Peoples R China
关键词： Chukrasia tabularis A. Juss.; Meliaceae; Limonoid; Triterpenoid; Acetylcholinesterase inhibitory activity
期刊名称：PHYTOCHEMISTRY LETTERS （ 影响因子：1.679； 五年影响因子：1.861 ）
ISSN： 1874-3900
年卷期： 2019 年 33 卷
页码：
收录情况： SCI
摘要： Three new limonoids named chuktabrin L (1), meliasenin Y (2), 11a-acetoxy-20,21,22,23-tetrahydro-23-oxoazadirone (3) and one new triterpenoid, named hispidol C (4), together with one known compound hispidol B (5) were isolated from the stems of Chukrasia tabularis A. Juss. Chuktabrin L (1) was a D-ring-opened 16-norphragmalin featuring a unique C-16 degraded polycyclic skeleton. Structures were elucidated by spectroscopic techniques of IR, HRESIMS and NMR. Compounds 1-5 were evaluated for acetylcholinesterase (AChE) inhibitory activity in vitro, however turned out inactive.
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