Genomic characterization of a novel virulent phage infecting the Aeromonas hydrophila isolated from rainbow trout (Oncorhynchus mykiss)
文献类型： 外文期刊
作者： Cao, Yongsheng 1 ; Li, Shaowu 1 ; Wang, Di 1 ; Zhao, Jingzhuang 1 ; Xu, Liming 1 ; Liu, Hongbai 1 ; Lu, Tongyan 1 ; Mou, 1 ;
作者机构： 1.Chinese Acad Fishery Sci, Heilongjiang River Fisheries Res Inst, Dept Aquaculture, Lab Fish Dis, Songfa St 43, Harbin 150070, Heilongjiang, Peoples R China
2.Tibet Acad Agr & Anim Husb Sci, Inst Fisheries Sci, 130 Jinzhu West Rd, Lhasa 850002, Tibet, Peoples R China
关键词： Bacteriophage; Aeromonas hydrophila; Genome analysis
期刊名称：VIRUS RESEARCH （ 影响因子：3.303； 五年影响因子：3.445 ）
ISSN： 0168-1702
年卷期： 2019 年 273 卷
页码：
收录情况： SCI
摘要： The virulent bacteriophage MJG that specifically infects Aeromonas hydrophila was isolated from a water sample from a river in Harbin, China. The genome of phage MJG was a double-stranded linear DNA with 45,057 bp, possessing 50.11% GC content. No virulence or resistance genes were found in the phage genome. Morphological observation, genomic characterization, and phylogenetic analysis indicated that MJG was closely related to phages belonging to the genus Sp6virus in the Podoviridae family. This phage is a novel member within Sp6virus that could infect and lyse A. hydrophila. This study could serve as a genomic reference of A. hydrophila phages and provide a potential agent for phage therapy.
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