文献类型： 外文期刊
作者： Huang, Sheng Zhuo 1 ; Duan, Lin Ping 2 ; Wang, Hao 1 ; Mei, Wen Li 1 ; Dai, Hao Fu 1 ;
作者机构： 1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Hainan Key Lab Res & Dev Nat Prod Li Folk Med, Haikou 571101, Hainan, Peoples R China
2.Nanjing Agr Univ, Coll Food Sci & Technol, Nanjing 210095, Jiangsu, Peoples R China
关键词： Kadsura coccinea; Schisandraceae; AChE inhibitor; triterpenoid
期刊名称：MOLECULES （ 影响因子：4.411； 五年影响因子：4.587 ）
ISSN：
年卷期： 2019 年 24 卷 19 期
页码：
收录情况： SCI
摘要： Two new triterpenoids, named kadsuricoccins A and B, together with three known ones, were isolated from the Li folk herb Heilaohu, the stems of Kadsura coccinea (Lem.) A. C. Smith, which was used for food and as a healthy supplement. Their structures were elucidated by comprehensive analyses of mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopic data. To search healthy components, an acetylcholinesterase (AChE) inhibitory activity test by Ellman's Method was conducted, kadsuricoccins A and B showed activity with the AChE inhibit index (AII) up to 68.96% +/- 0.19% and 57.8% +/- 0.11% at 94 nM (compared with positive control tacrine AII 79.80% +/- 0.20%, 9.4 nM), respectively.
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