文献类型： 外文期刊
作者： Yu, Haiqian 1 ; Hoefert, Simon-Patrick 2 ; Moussa, Mariam 1 ; Janiak, Christoph 2 ; Mueller, Werner E. G. 3 ; Umeok 1 ;
作者机构： 1.Heinrich Heine Univ Dusseldorf, Inst Pharmaceut Biol & Biotechnol, Univ Str 1, D-40225 Dusseldorf, Germany
2.Heinrich Heine Univ Dusseldorf, Inst Inorgan & Struct Chem, Univ Str 1, D-40225 Dusseldorf, Germany
3.Univ Med Johannes Gutenberg Univ Mainz, Inst Physiol Chem, D-55128 Mainz, Germany
4.Nnamdi Azikiwe Univ, Dept Pharmaceut & Med Chem, Awka, Nigeria
5.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Key Lab Biol & Genet Resources Trop Crops, Minist Agr, Haikou 571101, Hainan, Peoples R China
关键词： Phomopsis sp.; Endophytic fungus; Polyketide; Peptide
期刊名称：TETRAHEDRON LETTERS （ 影响因子：2.415； 五年影响因子：2.036 ）
ISSN： 0040-4039
年卷期： 2019 年 60 卷 51 期
页码：
收录情况： SCI
摘要： Three new polyketides, phomopones A-C (1-3), one new cyclic tetrapeptide, 18-hydroxydihydrotentoxin (4), and a new amide, 6-hydroxyenamidin (5) together with a known derivative, enamindin (6) were obtained from the endophytic fungus Phomopsis sp. D15a2a isolated from the plant Alternanthera bettzickiana. The structures of the new compounds were elucidated by 1D, 2D NMR and HRMS data. The absolute configurations of the isolated metabolites were determined either by X-ray crystallography, Marfey's method or by converting the compounds to Mosher esters. (C) 2019 Elsevier Ltd. All rights reserved.
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