Streptoxamine, an unprecedented benzoisoindole-deferoxamine hybrid from the locust-derived Streptomyces sp HKHCa2
文献类型： 外文期刊
作者： Guo, Zhi Kai 1 ; Wang, Rong 2 ; Chen, Fu Xiao 2 ; Liu, Tian Mi 3 ;
作者机构： 1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Minist Agr, Key Lab Biol & Genet Resources Trop Crops, Haikou 571101, Hainan, Peoples R China
2.Hainan Acad Ocean & Fisheries Sci, Haikou 570203, Hainan, Peoples R China
3.Hainan Testing Ctr Qual & Safety Aquat Prod, Haikou 570206, Hainan, Peoples R China
关键词： Streptoxamine; Streptomyces sp HKHCa2; Locust; Antibacterial activity
期刊名称：FITOTERAPIA （ 影响因子：2.882； 五年影响因子：3.202 ）
ISSN： 0367-326X
年卷期： 2018 年 127 卷
页码：
收录情况： SCI
摘要： An unusual benzoisoindole-deferoxamine hybrid, streptoxamine (1), has been isolated from the ethyl acetate crude extract of the fermentation broth of a locust-associated actinomycete, Streptomyces sp. HKHCa2, which was isolated from an insect, Oxya chinensis. The structure of this secondary metabolite was elucidated on the basis of its one-dimension, two-dimension NMR, and mass spectroscopic data. This natural product features a hybrid pattern of a benzoisoindole with an "iron carrier" deferoxamine B through C-N linkage. Compound 1 showed weak antibacterial activity against the gram-positive bacteria, Staphylococcus aureus and Mycobacterium smegmatis.
- 相关文献
作者其他论文 更多>>
-
Carbazomycins I and J, two novel carbazole alkaloids isolated from Saccharopolyspora phattalungensis
作者：Wang, Wen;Zhao, Er Juan;Peng, Ting;Yan, Zhang Yuan;Jiao, Rui Hua;Guo, Zhi Kai;Guo, Zhi Kai
关键词：Microbial Natural Products; Carbazole alkaloids; Structural elucidation; Gene cluster; Biosynthesis pathway
-
Critical Secondary Metabolites Confer the Broad-Spectrum Pathogenic Fungi Resistance Property of a Marine-Originating Streptomyces sp. HNBCa1
作者：Xiong, Zijun;Wu, Weicheng;Qi, Min;Zhang, Shiqing;Guo, Zhikai;Xia, Tengfei;Zheng, Daojun;Wu, Weicheng;Qi, Min;Li, Jitao;Wang, Rong;Yang, Yang;Lin, Shuangjun
关键词：broad-spectrum resistance; secondary metabolites; pathogenic fungi; antifungal activity; biocontrol
-
Secondary Metabolites with Agricultural Antagonistic Potential from Aspergillus sp. ITBBc1, a Coral-Associated Marine Fungus
作者：Abulaizi, Ailiman;Ge, Huiming;Wang, Rong;Xiong, Zijun;Zhang, Shiqing;Guo, Zhikai;Wang, Rong;Xiong, Zijun;Zhang, Shiqing;Guo, Zhikai;Wang, Rong;Li, Yuanchao
关键词：Aspergillus sp.; marine fungi; secondary metabolites; phytotoxic activity
-
Isolation and biological activity of six new polyketide and terpenoid derivatives from Neopestalotiopsis Clavispora AL01
作者：Abulaizi, Ailiman;Wang, Zi Ru;Ge, Hui Ming;Abulaizi, Ailiman;Xiong, Zi Jun;Zhang, Shi Qing;Yuan, Jing Zhe;Chen, Bi-Ting;Guo, Zhi Kai;Abulaizi, Ailiman;Xiong, Zi Jun;Zhang, Shi Qing;Yuan, Jing Zhe;Chen, Bi-Ting;Guo, Zhi Kai;Yang, Yang;Yang, Yang
关键词：Natural products; Fungus; Neopestalotiopsis clavispora; Secondary metabolites; Biological activity
-
Natural Products and Biological Activity from Actinomycetes Associated with Marine Algae
作者：Xiong, Zijun;Zhang, Shiqing;Ma, Shuai;Guo, Zhikai;Xiong, Zijun;Zhang, Shiqing;Ma, Shuai;Guo, Zhikai;Wang, Rong;Xia, Tengfei
关键词：actinomycetes; marine algae; secondary metabolite; bioactive compound
-
Nagimycins A and B, Antibacterial Ansamycin-Related Macrolactams from Streptomyces sp. NA07423
作者：Guo, Zhi Kai;Abulaizi, Ailiman;Xiong, Zi Jun;Zhang, Shi Qing;Guo, Zhi Kai;Abulaizi, Ailiman;Xiong, Zi Jun;Zhang, Shi Qing;Wang, Yong Chao;Tan, Ying Zi;Abulaizi, Ailiman;Shi, Jing;Yang, Yang;Yang, La Ying;Yang, Yang;Yang, La Ying
关键词：
-
Seven drimane-type sesquiterpenoids from an earwig-associated Aspergillus sp.
作者：Salman, Khan;Zhu, Hongjie;Sun, Ziqian;Wang, Lan;Jiao, Ruihua;Guo, Zhikai;Li, Yilin;Guo, Zhikai;Li, Yilin;Wang, Rong
关键词：Fungus; Sesquiterpenoids; Drimane-type; Antibacterial; Cytotoxic; Aspergillus sp
