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ERGOSTANE STEROIDS FROM Coprinus setulosus

文献类型: 外文期刊

作者: Ma, Qing-Yun 1 ; Yang, Shuang 1 ; Huang, Sheng-Zhuo 1 ; Kong, Fan-Dong 1 ; Xie, Qing-Yi 1 ; Dai, Hao-Fu 1 ; Yu, Zhi-Fa 1 ;

作者机构: 1.CATAS, Key Lab Biol & Genet Resources Trop Crops, Inst Trop Biosci & Biotechnol, Haikou 571101, Hainan, Peoples R China

2.Nanjing Agr Univ, Coll Food Sci & Technol, Nanjing 210095, Jiangsu, Peoples R China

关键词: Coprinus setulosus; Coporinaceae; steroids; AChE inhibitory activity

期刊名称:CHEMISTRY OF NATURAL COMPOUNDS ( 影响因子:0.809; 五年影响因子:0.708 )

ISSN: 0009-3130

年卷期: 2018 年 54 卷 4 期

页码:

收录情况: SCI

摘要: One new ergostane steroid, ergosta-4,6,8,22E-tetraen-11 beta-ol (1), together with five known analogues (2-6), was isolated from the fruiting bodies of Coprinus setulosus for the first time. Their structures were elucidated by analysis of 1D and 2D spectroscopic data as well as MS. The inhibitory activity of these isolates against acetylcholinesterase (AChE) showed that compound 1 exhibited weak inhibitory activity.

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