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New secondary metabolites from the endophytic fungus Fusarium sp HP-2 isolated from "Qi-Nan" agarwood

文献类型: 外文期刊

作者: Xiao, Wen-Jie 1 ; Chen, Hui-Qin 1 ; Wang, Hao 1 ; Cai, Cai-Hong 1 ; Mei, Wen-Li 1 ; Dai, Hao-Fu 1 ;

作者机构: 1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Minist Agr, Key Lab Biol & Genet Resources Trop Crops, Haikou 571101, Hainan, Peoples R China

关键词: "Qi-Nan" agarwood; Endophytic fungus; Fusarium sp.; Furan derivative; Naphthalenone derivative

期刊名称:FITOTERAPIA ( 影响因子:2.882; 五年影响因子:3.202 )

ISSN: 0367-326X

年卷期: 2018 年 130 卷

页码:

收录情况: SCI

摘要: A novel pyrone derivative (1) bearing two fused five-member rings, together with two new naphthalenone derivatives (2, 3), as well as two known compounds (4, 5) were obtained from the endophytic fungus Fusarium sp. HP-2, which was isolated from "Qi-Nan" agarwood. The structures of the new compounds were elucidated by analysis of 1D and 2D NMR, and by HRESIMS spectra, as well as by comparison with the literature. Bioactivity results indicated that compound 3 showed weak acetylcholinesterase inhibitory activity.

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