A new cytochalasin derivative from the mangrove-derived endophytic fungus Xylaria sp. HNWSW-2
文献类型： 外文期刊
作者： Wang, Pei 1 ; Cui, Yan 1 ; Cai, Cai-Hong 1 ; Kong, Fang-Dong 1 ; Chen, Hui-Qin 1 ; Zhou, Li-Man 1 ; Song, Xin-Ming; Me 1 ;
作者机构： 1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Key Lab Biol & Genet Resources Trop Crops, Minist Agr, Haikou 571101, Hainan, Peoples R China
2.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Key Lab Biol & Genet Resources Trop Crops, Minis
关键词： Mangrove; endophytic fungus; cytochalasin derivative; AChE inhibitory activity; -glycosidase inhibitory activity
期刊名称：JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH （ 影响因子：1.569； 五年影响因子：1.598 ）
ISSN： 1028-6020
年卷期： 2018 年 20 卷 10 期
页码：
收录情况： SCI
摘要： A new cytochalasin derivative xylarisin B (1), together with four known compounds astropyrone (2), guaidiol (3), xylaropyrone B (4), and xylaropyrone C (5), were isolated from the fermentation broth of Xylaria sp. HNWSW-2. Their structures were elucidated by spectroscopic data. Among them, compounds 2 and 3 at a concentration of 50g/ml showed weak inhibitory activity against AChE with inhibition rates of 10.4 and 12.9%, respectively. In addition, compound 2 also exhibited inhibitory activity against -glycosidase with inhibition rate of 77.0% at a concentration of 0.25mg/ml. [GRAPHICS] .
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