Genome-wide characterization, phylogenetic and expression analysis of Galectin gene family in Golden pompano Trachinotus ovatus
文献类型： 外文期刊
作者： Pan, Jin-Min 1 ; Liang, Yu 1 ; Zhu, Ke-Cheng 1 ; Guo, Hua-Yang 1 ; Liu, Bao-Suo 1 ; Zhang, Nan 1 ; Xian, Lin 1 ; Zhu, Teng-Fei 1 ; Zhang, Dian-Chang 1 ;
作者机构： 1.Minist Agr & Rural Affairs, Key Lab South China Sea Fishery Resources Exploita, Guangzhou, Guangdong, Peoples R China
2.Chinese Acad Fishery Sci, South China Sea Fisheries Res Inst, Guangzhou, Guangdong, Peoples R China
3.Guangdong Prov Engineer Technol Res Ctr Marine Bio, Guangzhou, Guangdong, Peoples R China
4.Sanya Trop Fisheries Res Inst, Sanya, Peoples R China
5.Chinese Acad Fishery Sci, Shenzhen Base South China Sea Fisheries Res Inst, Shenzhen, Guangdong, Peoples R China
关键词： Galectins; Golden pompano; subcellular localization; protein function; bacterial agglutination
期刊名称：FRONTIERS IN IMMUNOLOGY （ 影响因子：5.7； 五年影响因子：6.8 ）
ISSN： 1664-3224
年卷期： 2024 年 15 卷
页码：
收录情况： SCI
摘要： Galectins (Gals) are a type of S-type lectin that are widespread and evolutionarily conserved among metazoans, and can act as pattern recognition receptors (PRRs) to recognize pathogen-associated molecular patterns (PAMPs). In this study, 10 Gals (ToGals) were identified in the Golden pompano (Trachinotus ovatus), and their conserved domains, motifs, and collinearity relationships were analyzed. The expression of ToGals was regulated following infection to Cryptocaryon irritans and Streptococcus agalactiae, indicating that ToGals participate in immune responses against microbial pathogens. Further analysis was conducted on one important member, Galectin-3, subcellular localization showing that ToGal-3like protein is expressed both in the nucleus and cytoplasm. Recombinant protein obtained through prokaryotic expression showed that rToGal-3like can agglutinate red blood cells of rabbit, carp and golden pompano and also agglutinate and kill Staphylococcus aureus, Bacillus subtilis, Vibrio vulnificus, S. agalactiae, Pseudomonas aeruginosa, and Aeromonas hydrophila. This study lays the foundation for further research on the immune roles of Gals in teleosts.
- 相关文献
作者其他论文 更多>>
-
Deciphering Trachinotus ovatus resistance to Streptococcus agalactiae:GWAS :GWAS identification of key SNPs and candidate genes
作者：Sun, Yi-Yao;Gao, Jie;Liu, Bao-Suo;Zhang, Nan;Guo, Hua-Yang;Zhu, Ke-Cheng;Xian, Lin;Zhang, Dian-Chang;Sun, Yi-Yao;Liu, Bao-Suo;Zhang, Nan;Guo, Hua-Yang;Zhu, Ke-Cheng;Xian, Lin;Zhang, Dian-Chang;Liu, Bao-Suo;Zhang, Nan;Zhu, Ke-Cheng;Zhang, Dian-Chang;Gao, Jie
关键词：GWAS; Trachinotus ovatus; Streptococcus agalactiae; SNP
-
Functional Characterization of Galectin-8 from Golden Pompano Trachinotus ovatus Reveals Its Broad-Spectrum Antimicrobial Activity
作者：Pan, Jin-Min;Gao, Jie;Liu, Ming Jian;Zhu, Ke-Cheng;Guo, Hua-Yang;Liu, Bao-Suo;Zhang, Nan;Zhang, Dian-Chang;Zhu, Ke-Cheng;Liu, Bao-Suo;Zhang, Nan;Zhang, Dian-Chang;Zhu, Ke-Cheng;Guo, Hua-Yang;Liu, Bao-Suo;Zhang, Nan;Zhang, Dian-Chang;Pan, Jin-Min;Gao, Jie
关键词：
Galectin-8 ; Antibacterial activity;Trachinotus ovatus ;Streptococcus agalactiae -
Chromosome-level genome assembly and annotation of the White-spotted spinefoot Siganus canaliculatus
作者：Huang, Xiaolin;Xian, Lin;Yang, Yukai;Zhang, Dianchang;Huang, Xiaolin;Xian, Lin;Yang, Yukai;Zhang, Dianchang;Huang, Xiaolin;Yang, Yukai;Zhang, Dianchang;Lu, Yanke;Zhang, Hui;Huang, Shiting;Wang, Lei;Li, Chao;Xian, Lin
关键词：
-
Gut microbiome composition likely affects the growth of Trachinotus ovatus by influencing the host's metabolism
作者：Wu, Chen-Xu;Zhang, Dian-Chang;Wu, Chen-Xu;Liu, Bao-Suo;Guo, Hua-Yang;Zhu, Teng-Fei;Xian, Lin;Zhang, Nan;Zhu, Ke-Cheng;Zhang, Dian-Chang;Guo, Hua-Yang;Zhang, Nan;Zhu, Ke-Cheng;Zhang, Dian-Chang;Liu, Bao-Suo;Zhang, Nan;Zhu, Ke-Cheng;Zhang, Dian-Chang;Liu, Bao-Suo;Zhang, Dian-Chang
关键词：Trachinotus ovatus; Growth differences; Gut microbiota; Interspecies interactions
-
Identification and functional analysis of glutathione S-transferase gene family in Trachinotus ovatus: Transcriptomic response to environmental and pathogenic stress
作者：Zhou, Jia-Mei;Zhang, Tian-Yue;Zhou, Jia-Mei;Zhu, Teng-Fei;Guo, Hua-Yang;Xian, Lin;Liu, Bao-Suo;Zhang, Nan;Zhang, Tian-Yue;Zhu, Ke-Cheng;Zhang, Dian-Chang;Zhu, Teng-Fei;Guo, Hua-Yang;Xian, Lin;Zhang, Nan;Zhu, Ke-Cheng;Zhang, Dian-Chang;Liu, Bao-Suo;Zhang, Nan;Zhu, Ke-Cheng;Zhang, Dian-Chang;Liu, Bao-Suo
关键词：Glutathione S-transferase; Trachinotus ovatus; Hypoxia stress; Pathogenic stress
-
SNPs in the Galectin-8 gene of Acanthopagrus latus have been found to be associated with resistance trait to Streptococcus iniae
作者：Pan, Jin-Min;Guo, Hua-Yang;Liu, Bao-Suo;Zhang, Nan;Xian, Lin;Zhu, Teng-Fei;Zhu, Ke-Cheng;Zhang, Dian-Chang;Pan, Jin-Min;Guo, Hua-Yang;Liu, Bao-Suo;Zhang, Nan;Xian, Lin;Zhu, Teng-Fei;Zhu, Ke-Cheng;Zhang, Dian-Chang;Pan, Jin-Min;Guo, Hua-Yang;Liu, Bao-Suo;Zhang, Nan;Xian, Lin;Zhu, Teng-Fei;Zhu, Ke-Cheng;Zhang, Dian-Chang
关键词：Acanthopagrus latus; Streptococcus iniae; SNPs; Galectin-8
-
Early development of vertebral column and appendicular skeleton in Naozhou Larimichthys crocea (Richardson, 1846)
作者：Liu, Bo-Wen;Sun, Jin-Hui;Liu, Bo-Wen;Guo, Hua-Yang;Liu, Bao-Suo;Zhang, Nan;Zhu, Ke-Cheng;Zhang, Dian-Chang;Guo, Hua-Yang;Liu, Bao-Suo;Zhang, Nan;Zhu, Ke-Cheng;Zhang, Dian-Chang;Yan, Kuo-Qiu;Qin, Hai-Peng
关键词：appendicular skeleton;
Laramichthys crocea ; larval and juvenile development; skeletal staining; vertebral column
