Determining b-lactam antibiotics in aquaculture products by modified QuECHERS combined with ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS)
文献类型： 外文期刊
作者： Li, Lichun 1 ; Yin, Yi 1 ; Zheng, Guangming 1 ; Liu, Shugui 1 ; Zhao, Cheng 1 ; Ma, Lisha 1 ; Shan, Qi 1 ; Dai, Xiaoxin 1 ; Wei, Linting 1 ; Lin, Jiawei 1 ; Xie, Wenping 1 ;
作者机构： 1.Chinese Acad Fishery Sci, Pearl River Fisheries Res Inst, Lab Qual & Safety Risky Assessment Aquat Prod, Minist Agr, Guangzhou 510380, Peoples R China; Chinese Acad Fishery Sci, Pearl River Fisheries Res Inst, Key Lab Recreat Fisheries Res, Minist Agr, Guangzhou 510380, Peoples R China; Key Lab Aquat Anim Immune Technol Guangdong Prov, Guangzhou 510380, Peoples R China
关键词： QuECHERS; UHPLC-MS; MS; Aquaculture products; P-lactam antibiotic
期刊名称：ARABIAN JOURNAL OF CHEMISTRY （ 影响因子：6.212； 五年影响因子：5.913 ）
ISSN： 1878-5352
年卷期： 2022 年 15 卷 7 期
页码：
收录情况： SCI
摘要： In this study, a multi-residue determination method of QuECHERS combined with UHPLC-MS/MS was developed to determine nine P-lactam antibiotics (penicillin G, amoxicillin, ampicillin, cephalexin, cefquinome, ceftiofur, cefazolin, cephapirin, cefuroxime) in aquaculture products. All the nine P-lactam antibiotics exhibited excellent linearity within the range of 2.0 & ndash; 200 ng/mL (cefuroxime: 5.0 & ndash;200 ng/mL, r greater than 0.999), while the limits of detection (LODs) and quantification (LOQs) were 2.0 & ndash;5.0 & micro;g/kg and 5.0 & ndash;10.0 & micro;g/kg, respectively. The recoveries of this method in five aquaculture products (Penaeus Orientalis, Cyprinus Carpio, Channa Argus, Aristichthys Nobilis, and Ctenopharyngodon Idella) ranged from 85.4% to 113.3% and the intra-day and inter-day precisions (%RSDs) were less than 15%. The results suggested the feasibility of this method as a rapid, simple, and accurate approach for determining the residues of the P-lactam antibiotics in aquaculture products. (c) 2022 The Author(s). Published by Elsevier B.V. on behalf of King Saud University. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
- 相关文献
作者其他论文 更多>>
-
Residue Behavior and Risk Assessment of Diazepam and Its Metabolites in Crucian Carp (Carassius auratus) After Oral Administration
作者：Shan, Qi;Zhou, Hao;Lin, Jiawei;Li, Lichun;Yin, Yi;Shan, Qi;Zhou, Hao;Lin, Jiawei;Li, Lichun;Yin, Yi;Shan, Qi;Zhou, Hao;Lin, Jiawei;Li, Lichun;Yin, Yi;Huang, Xiaosheng;Ye, Shucai;Li, Jianqiang;Xu, Feng
关键词：crucian carp; diazepam; residue behavior; risk assessment; tissue distribution
-
Rapid determination of fipronil and its metabolites in aquatic products by modified QuEChERS method coupled with UPLC-MS/MS
作者：Ma, Lisha;Zhou, Hao;Lin, Jiawei;Yin, Yi;Shan, Qi;Li, Lichun;Wei, Ningting;Dai, Xiaoxin;Zhao, Cheng;Liu, Shugui
关键词：Fipronil; aquatic products; UPLC-MS/MS; QuEChERS; risk assessment; analysis methods
-
Determination of diazepam and its active metabolites in aquatic products and aquaculture environments using modified QuEChERS-based UPLC-MS/MS
作者：Zhou, Hao;Wei, Linting;Lin, Jiawei;Zhao, Cheng;Shan, Qi;Wang, Qing;Yin, Yi;Xu, Feng;Mei, Huiqing;Mu, Yingchun
关键词：
-
Highly dispersed single-atom Fe and Fe3O4 clusters anchored hierarchical-pore carbon as efficient persulfate activation catalyst
作者：Lin, Jiawei;Zhou, Hao;Wei, Linting;Zhao, Cheng;Dai, Xiaoxin;Wang, Qing;Zheng, Guangming;Yin, Yi;Zhang, Hongfeng;Hu, Yongyou
关键词：MIL-88B pyrolysis; Acid etching; Single-Atom Fe; Atomic clusters; Hierarchical-pore Carbon
-
Simultaneous determination of enantiomer residues of metalaxyl and its metabolite metalaxyl acid in animal muscle tissues by chiral liquid chromatography-tandem mass spectrometry
作者：Zhou, Hao;Shan, Qi;Zhao, Cheng;Zheng, Guangming;Li, Lichun;Ma, Lisha;Yin, Yi;He, Limin;Zhang, Meiyu;Xu, Feng
关键词：Metalaxyl; Metabolite residue; Solid phase extraction; Chiral LC-MS/MS; Muscle tissues; Stereoselective analysis
-
Pharmacokinetics, withdrawal period and risk assessment of enrofloxacin in the northern snakehead (Channa argus) following bath administration
作者：Zhang, Meiling;Zheng, Guangming;Yin, Yi;Zhou, Hao;Ma, Lisha;Li, Lichun;Lin, Jiawei;Liu, Shugui;Zhao, Cheng;Dai, Xiaoxin;Wei, Linting;Shan, Qi;Shan, Qi
关键词：enrofloxacin; northern snakehead; pharmacokinetics; risk assessment; withdrawal period
-
Pharmacokinetics and residue elimination of metalaxyl enantiomers in snakehead (Channa argus)
作者：Zhou, Hao;Shan, Qi;Huang, Heqing;Zhang, Meiling;Liu, Shugui;Lin, Jiawei;Ma, Lisha;Zheng, Guangming;Li, Lichun;Zhao, Cheng;Dai, Xiaoxin;Wei, Linting;Yin, Yi;Zhang, Meiyu;Zhou, Hao;Shan, Qi;Zheng, Guangming;Yin, Yi;Zhou, Hao;Shan, Qi;Zheng, Guangming;Yin, Yi;Huang, Heqing;Zhang, Meiling
关键词：Metalaxyl enantiomers; Stereoselectivity pharmacokinetics; Residues elimination; Liquid chromatography-tandem mass spectrometry; Snakehead(Channaargus)
