Comprehensive Analysis of Circular RNAs to Decipher the Potential Roles in Blind-Side Hypermelanosis in Chinese Tongue Sole (Cynoglossus semilaevis)
文献类型： 外文期刊
作者： Hu, Yuanri 1 ; Li, Yangzhen 1 ; Cheng, Peng 1 ; Chen, Songlin 1 ;
作者机构： 1.Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Inst, Shandong Key Lab Marine Fisheries Biotechnol & Gen, Qingdao, Peoples R China
2.Shanghai Ocean Univ, Natl Demonstrat Ctr Expt Fisheries Sci Educ, Shanghai, Peoples R China
3.Pilot Natl Lab Marine Sci & Technol Qingdao, Lab Marine Fisheries Sci & Food Prod Proc, Qingdao, Peoples R China
关键词： circRNA; ceRNA network; body color; ncRNA; flatfish; malpigmentation
期刊名称：FRONTIERS IN MARINE SCIENCE （ 影响因子：5.247； 五年影响因子：5.72 ）
ISSN：
年卷期： 2022 年 9 卷
页码：
收录情况： SCI
摘要： Blind-side hypermelanosis is an emerging concern across the flatfish aquaculture industry including Chinese tongue sole (Cynoglossus semilaevis). Circular RNAs (circRNAs) as endogenous non-coding RNAs have been acknowledged to play important roles in various biological processes. However, the underlying regulatory mechanisms of circRNAs involved in flatfish blind-side hypermelanosis remain unclear. In this study, to profile the circRNA expression pattern and circRNA-microRNA-messenger RNA (mRNA) network, high-throughput sequencing was performed by using blind-side normal and hypermelanotic skins of tongue sole. A total of 73 differentially expressed circRNAs were identified, and the competing endogenous RNA (ceRNA) network was constructed. Furthermore, circRNA host genes and mRNAs involved in ceRNA network were subjected to Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes enrichment analyses. Several GO terms and pathways of biological significance were identified and well addressed the generation of blind-side hypermelanosis to some extent. These interesting results extend the understanding of the functional profile of circRNAs and yield valuable insights into the molecular regulatory mechanisms of hypermelanosis in flatfish.
- 相关文献
作者其他论文 更多>>
-
Decoding the fish genome opens a new era in important trait research and molecular breeding in China
作者：Zhou, Qian;Wang, Jialin;Chen, Zhangfan;Wang, Na;Li, Ming;Wang, Lei;Si, Yufeng;Lu, Sheng;Cui, Zhongkai;Liu, Xuhui;Chen, Songlin;Zhou, Qian;Wang, Jialin;Chen, Zhangfan;Wang, Na;Li, Ming;Wang, Lei;Si, Yufeng;Lu, Sheng;Cui, Zhongkai;Liu, Xuhui;Chen, Songlin;Li, Jiongtang
关键词：fish genomics; economic traits; genomic selection; genome editing; genomic breeding
-
Integrative omics reveals clues as to why Cynoglossus semilaevis pseudomales produce no W sperm
作者：Zhang, Yaqun;Wang, Liping;Xu, Feng;Ye, Zhan;Li, Hengde;Zhang, Yaqun;Wang, Liping;Xu, Feng;Ye, Zhan;Li, Hengde;Wang, Liping;Xu, Feng;Ye, Zhan;Chen, Songlin;Chen, Songlin;Chen, Songlin;Li, Hengde
关键词：Spermatogenesis; Transcriptome; Proteome; Ubiquitination; Pseudomale; Cynoglossus semilaevis
-
Multi-organ transcriptomic profiles and gene-regulation network underlying vibriosis resistance in tongue sole
作者：Chen, Quanchao;Hu, Guobin;Ma, Xinran;Wang, Jie;Shi, Meng;Chen, Songlin;Zhou, Qian;Chen, Songlin;Zhou, Qian
关键词：
-
Transcriptome Analysis Reveals the Immunosuppression in Tiger Pufferfish (Takifugu rubripes) under Cryptocaryon irritans Infection
作者：Chi, Yong;Chen, Songlin;Li, Yangzhen;Mukiibi, Robert;Robledo, Diego;Li, Yangzhen;Mukiibi, Robert;Robledo, Diego;Li, Yangzhen;Zhang, Hongxiang;Zhang, Haien;Li, Weidong;Li, Yangzhen;Zhang, Hongxiang;Robledo, Diego
关键词：fugu; RNA-seq; immune response; parasite; aquaculture
-
Characterization of emopamil binding protein (Cs-ebp) reveals its potential role in cholesterol biosynthesis and growth performance of Chinese tongue sole
作者：Chen, Zhangfan;Li, Xihong;Wang, Na;Chen, Songlin;Chen, Zhangfan;Li, Xihong;Cheng, Peng;Mai, Jiaqi;Sun, Yuqi;Wang, Jiacheng;Shi, Rui;Zhang, Qi;Wang, Na;Chen, Songlin;Chen, Zhangfan;Li, Xihong;Cheng, Peng;Mai, Jiaqi;Sun, Yuqi;Wang, Jiacheng;Shi, Rui;Zhang, Qi;Wang, Na;Chen, Songlin;Wang, Na;Chen, Songlin
关键词：Chinese tongue sole; Emopamil-binding protein (EBP); Cholesterol biosynthesis; Sexual size dimorphism; Ovarian development
-
Development of a 20 K SNP array for the leopard coral grouper, Plectropomus leopardus
作者：Zhou, Qian;Lu, Sheng;Liu, Yang;Chen, Songlin;Zhou, Qian;Lu, Sheng;Liu, Yang;Chen, Songlin;Zhou, Bo;Zhou, Qian;Chen, Songlin
关键词：Leopard coral grouper; Plectropomus leopardus; SNP array; Aquaculture
-
Accurate genomic selection using low-density SNP panels preselected by maximum likelihood estimation
作者：Qu, Shiyu;Lu, Sheng;Liu, Yang;Li, Ming;Chen, Songlin;Qu, Shiyu;Lu, Sheng;Liu, Yang;Li, Ming;Chen, Songlin;Qu, Shiyu;Lu, Sheng;Liu, Yang;Li, Ming;Chen, Songlin;Chen, Songlin
关键词：Maximum likelihood estimation; Genomic selection; SNP pre-selection; MLE-rank
