文献类型： 外文期刊
作者： Luo, Ke 1 ; Dai, Rong-Ji 1 ; Zeng, Yan-Bo 1 ; Chang, Wen-Jun 2 ; Deng, Yu-Lin 1 ; Lv, Fang 1 ;
作者机构： 1.Beijing Inst Technol, Sch Life Sci, Beijing Key Lab Separat & Anal Biomed & Pharmaceut, Beijing 100081, Peoples R China
2.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Hainan Prov Key Lab Funct Components Res & Utiliza, Haikou 571101, Peoples R China
关键词： Bupleurum marginatum; triterpenoid saponins; structural elucidation; anti-liver fibrotic activity
期刊名称：JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH （ 影响因子：1.7； 五年影响因子：1.7 ）
ISSN： 1028-6020
年卷期： 2024 年
页码：
收录情况： SCI
摘要： A new triterpenoid saponin (1), along with five known compounds (2-6), was isolated from Bupleurum marginatum Wall. ex DC, of which compounds 2-4 were obtained for the first time from this plant. The structures were confirmed by the analysis of 1D, 2D NMR, and HR-ESIMS data, and comparison with previous spectral data. Anti-liver fibrotic activities of the isolates were determined as proliferation inhibition of LPS-induced activation of HSC-T6 in vitro.
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