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A NEW BENZOPHENONE FROM Dobinea delavayi

文献类型: 外文期刊

作者: Cheng, Zhong-Quan 1 ; Yang, Dan 2 ; Ma, Qing-Yun 1 ; Yi, Xin-Hui 2 ; Zhou, Jun 3 ; Zhao, You-Xing 1 ;

作者机构: 1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China

2.Guilin Normal Coll, Guilin 541001, Peoples R China

3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China

关键词: Dobinea delavayi;benzophenone;dobiniside A

期刊名称:CHEMISTRY OF NATURAL COMPOUNDS ( 影响因子:0.809; 五年影响因子:0.708 )

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收录情况: SCI

摘要: A new benzophenone sesquiterpene dobiniside A (1), together with two known compounds, 4',6-dihydroxy-2,3',4-trimethoxybenzophenone (2) and mangiferin (3), were isolated from the root of Dobinea delavayi. The structure of the new compound was determined on the basis of spectroscopic analysis, including 1D, 2D NMR, and FAB-MS techniques as well as by comparison of the spectral data with those of related compounds reported in the literatures. Compounds 1-3 were screened for antitumor activity in vitro, and compound 3 was shown to possess anti-tumor activity with IC_(50) value of 7.4 X 10~(-5) μm for A-549.

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[1]Three New Sesquiterpenes with Cytotoxic Activity from Dobinea delavayi. Ma, Qing-Yun,Dai, Hao-Fu,Huang, Sheng-Zhuo,Zhao, You-Xing,Cheng, Zhong-Quan,Zhou, Jun,Cheng, Zhong-Quan,Yang, Dan,Yi, Xiang-Hui.

[2]Fatty acid synthase inhibitors of phenolic constituents isolated from Garcinia mangostana. Quan, Xiao Fang,Tian, Wei Xi,Ma, Xiao Feng,Jiang, He Zhong,Hu, Jiang Miao,Wang, Peng Cheng,Huang, Sheng Zhuo,Cheng, Zhong Quan,Liang, Wen Juan,Zhou, Jun,Zhao, You Xing,Zhao, You Xing. 2010

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