Lanostane triterpenoids with cytotoxic activities from the fruiting bodies of Ganoderma hainanense
文献类型： 外文期刊
作者： Ma, Qing-Yun 1 ; Luo, Ying 1 ; Huang, Sheng-Zhuo 1 ; Guo, Zhi-Kai 1 ; Dai, Hao-Fu 1 ; Zhao, You-Xing 1 ;
作者机构： 1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China
关键词： Cytotoxicities;Ganoderma hainanense;Lanostane triterpenoids
期刊名称：JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH （ 影响因子：1.569； 五年影响因子：1.598 ）
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收录情况： SCI
摘要： Twelve lanostane triterpenoids (1-12) including a new one 16α,26-dihydroxylanosta-8,24-dien-3-one (1) were isolated from the fruiting bodies of Ganoderma hainanense. The structure of the new compound was elucidated by 1D and 2D NMR and MS spectroscopic analyses. All isolates were evaluated for their cytotoxicities against human tumor cell lines K-562, SMMC-7721, and SGC-7901 and five compounds (1, 2, 5,7, and 9) showed definite cytotoxicities against K-562 cell line. Meanwhile, compounds 2, 5,7, and 9 exhibited cytotoxic activities against SMMC-7721 and SGC-7901 cell lines.
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