Optimization of selenylation conditions for lycium barbarum polysaccharide based on antioxidant activity
文献类型： 外文期刊
作者： Qiu, Shulei 1 ; Chen, Jin 2 ; Chen, Xi 1 ; Fan, Qiang 3 ; Zhang, Cunshuai; Wang, Deyun 1 ; Li, Xiuping 1 ; Chen, Xingy 1 ;
作者机构： 1.Nanjing Agr Univ, Coll Vet Med, Inst Tradit Chinese Vet Med, Nanjing 210095, Jiangsu, Peoples R China
2.Jiangsu Acad Agr Sci, Natl Res Ctr Vet Biol Engn & Technol, Nanjing 210014, Peoples R China
3.Chin
关键词： Selenizing lycium barbarum polysaccharide;Free radical-scavenging rate;GSH-Px activity;SOD activity;MDA content
期刊名称：CARBOHYDRATE POLYMERS （ 影响因子：9.381； 五年影响因子：8.678 ）
ISSN：
年卷期：
页码：
收录情况： SCI
摘要： Lycium barbarum polysaccharide (LBP) was modified by HNO3-Na2SeO3 method according to L9(3~4) orthogonal design to obtain nine selenizing LBPs (sLBPs), sLBP1 -sLBPg. Their antioxidant activities in vitro were compared by free radical-scavenging test. sLBP6, sLBP8 and sLBPg presented stronger activity. In vivo test, 14-day-old chickens were injected respectively with sLBP6, sLBP8 and sLBP9 taking LBP as control, and serum GSH-Px and SOD activities and MDA content were determined. The results showed that three sLBPs could significantly enhance GSH-Px and SOD activities and decrease MDA content. The actions of sLBPs were significantly stronger than that of unmodified LBP. These results indicated that selenylation modification could significantly enhance the antioxidant activities of LBP, sLBP6 possessed the best efficacy and could be exploited into an antioxidant. The optimal modification conditions were 400 mg of sodium selenite for 500 mg of LBP, reaction temperature of 70 °C and reaction time of 6 h.
- 相关文献
作者其他论文 更多>>
-
Analysis of CVC1302-Mediated Enhancement of Monocyte Recruitment in Inducing Immune Responses
作者：Lu, Haiyan;Yu, Xiaoming;Hou, Liting;Zhang, Yuanpeng;Li, Lan;Qiao, Xuwen;Cheng, Haiwei;Du, Luping;Chen, Jin;Zheng, Qisheng;Hou, Jibo;Lu, Haiyan;Yu, Xiaoming;Hou, Liting;Zhang, Yuanpeng;Li, Lan;Qiao, Xuwen;Cheng, Haiwei;Du, Luping;Chen, Jin;Zheng, Qisheng;Hou, Jibo;Lu, Haiyan;Yu, Xiaoming;Hou, Liting;Zhang, Yuanpeng;Li, Lan;Qiao, Xuwen;Cheng, Haiwei;Du, Luping;Chen, Jin;Zheng, Qisheng;Hou, Jibo;Lu, Haiyan;Yu, Xiaoming;Hou, Liting;Zhang, Yuanpeng;Li, Lan;Qiao, Xuwen;Cheng, Haiwei;Du, Luping;Chen, Jin;Zheng, Qisheng;Hou, Jibo;Lu, Haiyan
关键词：CVC1302; monocyte; CXCL9; CXCL10; antigen
-
Conventional dendritic cells 2, the targeted antigen-presenting-cell, induces enhanced type 1 immune responses in mice immunized with CVC1302 in oil formulation
作者：Du, Luping;Lu, Haiyan;Qiao, Xuwen;Zhang, Yuanpeng;Hou, Liting;Yu, Xiaoming;Cheng, Haiwei;Chen, Jin;Zheng, Qisheng;Hou, Jibo;Du, Luping;Lu, Haiyan;Qiao, Xuwen;Zhang, Yuanpeng;Hou, Liting;Yu, Xiaoming;Cheng, Haiwei;Chen, Jin;Zheng, Qisheng;Hou, Jibo;Du, Luping;Lu, Haiyan;Qiao, Xuwen;Zhang, Yuanpeng;Hou, Liting;Yu, Xiaoming;Cheng, Haiwei;Chen, Jin;Zheng, Qisheng;Hou, Jibo;Tong, Guangzhi;Lu, Haiyan;Chen, Jin;Zheng, Qisheng
关键词：CVC1302; Oil formulation; Interfollicular region; Inflammatory niche; Th1 cells
-
Cistanche deserticola polysaccharide- functionalized dendritic fibrous nano-silica- based adjuvant for H 9 N 2 oral vaccine enhance systemic and mucosal immunity in chickens
作者：He, Jin;Lu, Xuanqi;Mao, Ningning;Zhu, Tianyu;Yu, Lin;Yu, Yaming;Peng, Song;Deng, Xiangwen;Hu, Bing;Wang, Deyun;Lu, Yu;Jiang, Wenming
关键词：Oral vaccine; Dendritic fibrous nano-silica; Adjuvant; Mucosal and systemic immunity; cetyltrimethylammonium bromide (CTAB); triethanolamine (TEA); sodium salicylate (Nasal); tetraethoxysilane (TEOS); 3-aminopropyltriethoxysilane (APTES); 1-Ethyl-3-(3-dimethylaminopropyl); carbodiimide(EDC & sdot;HOL); N-Hydroxy succinimide (NHS); Lipopolysaccharide (LPS); phytohaemagglutinin (PHA); Cistanche deserticola polysaccharide (CDP)
-
Matrine Ameliorates DSS-Induced Colitis by Suppressing Inflammation, Modulating Oxidative Stress and Remodeling the Gut Microbiota
作者：Mao, Ningning;Yu, Yaming;He, Jin;Yang, Yang;Liu, Zhenguang;Wang, Deyun;Mao, Ningning;Yu, Yaming;He, Jin;Yang, Yang;Liu, Zhenguang;Wang, Deyun;Lu, Yu
关键词：DSS; matrine; ulcerative colitis; Treg/Th17; gut microbiota
-
How does digital governance affect the level of domestic waste separation for rural residents? Empirical evidence from rural areas in Jiangsu Province, China
作者：Chen, Xi;Wang, Kai;Xing, Lirong;Lu, Jianzhen
关键词：digital governance; cadre-mass relationship; institutional trust; domestic waste separation; Jiangsu
-
Increases in Cellular Immune Responses Due to Positive Effect of CVC1302-Induced Lysosomal Escape in Mice
作者：Yu, Xiaoming;Zhang, Yuanyuan;Hou, Liting;Qiao, Xuwen;Zhang, Yuanpeng;Cheng, Haiwei;Lu, Haiyan;Chen, Jin;Du, Luping;Zheng, Qisheng;Hou, Jibo;Yu, Xiaoming;Zhang, Yuanyuan;Hou, Liting;Qiao, Xuwen;Zhang, Yuanpeng;Cheng, Haiwei;Lu, Haiyan;Chen, Jin;Du, Luping;Zheng, Qisheng;Hou, Jibo;Yu, Xiaoming;Zhang, Yuanyuan;Hou, Liting;Qiao, Xuwen;Zhang, Yuanpeng;Cheng, Haiwei;Lu, Haiyan;Chen, Jin;Du, Luping;Zheng, Qisheng;Hou, Jibo;Yu, Xiaoming;Zhang, Yuanyuan;Hou, Liting;Qiao, Xuwen;Zhang, Yuanpeng;Cheng, Haiwei;Lu, Haiyan;Chen, Jin;Du, Luping;Zheng, Qisheng;Hou, Jibo;Tong, Guangzhi
关键词：cross-presentation; cellular immunity; cytosolic pathways; lysosomal escape
-
Spatiotemporal evolution and driving factors of the coupling coordination between county land urbanization and grain production: the case of Jiangsu province, China
作者：Chen, Xi;Zhou, Junting;Xing, Lirong;Wang, Haitao;Lu, Jianzhen
关键词：land urbanization; grain production; coupling coordination degree (CCD); spatiotemporal evolution; space Durbin model (SDM); Jiangsu province
