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Carbazole alkaloids from the peels of Clausena lansium

文献类型: 外文期刊

作者: Deng, Hui-Dong 1 ; Mei, Wen-Li 1 ; Wang, Hui 1 ; Guo, Zhi-Kai 1 ; Dong, Wen-Hua 1 ; Wang, Hao 1 ; Li, Shao-Peng; Dai, 1 ;

作者机构: 1.Chinese Acad Trop Agr Sci, Key Lab Biol & Genet Resources Trop Crops, Minist Agr, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China

2.Hainan Un

期刊名称:JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH ( 影响因子:1.569; 五年影响因子:1.598 )

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收录情况: SCI

摘要: A new carbazole alkaloid, claulansine K (1), together with six known carbazole alkaloids (2-7), was isolated from the peels of Clausena lansium (Lour.) Skeels. The new compound was elucidated using a combination of ID and 2D NMR (HMQC, HMBC, COSY, and ROESY) techniques, and HR-EI-MS analyses. Compound 1 showed in vitro alpha-glucosidase inhibitory activity with the IC50 value of 0.11 mM. Compound 2 exhibited moderate antibacterial activity against Staphylococcus aureus with the diameter of inhibition zone of 14.2 mm.

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