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Two New Guaiane Sesquiterpenoids from Daphne holosericea (Diels) Hamaya

文献类型： 外文期刊

作者： Ma, Qing-Yun 1 ; Chen, Yi-Chun 2 ; Huang, Sheng-Zhuo 1 ; Guo, Zhi-Kai 1 ; Dai, Hao-Fu 1 ; Hua, Yan 2 ; Zhao, You-Xing 1 ;

作者机构： 1.Chinese Acad Trop Agr Sci, Inst Trop Bioscience & Biotechnol, Key Lab Biol & Genet Resources Trop Crops, Minist Agr, Haikou 571101, Hainan, Peoples R China

2.Southwest Forestry Univ, Coll Forestry, Kunming 650224, Yunnan, Peoples R China

关键词： Thymelaeaceae;Daphne holosericea;guaiane sesquiterpenoids;acetylcholinesterase inhibition

期刊名称：MOLECULES （ 影响因子：4.411； 五年影响因子：4.587 ）

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收录情况： SCI

摘要： Two new sesquiterpenoids with guaiane skeletons-holosericin A (1) and holosericin B (2)-were isolated from the medicinal plant Daphne holosericea (Diels) Hamawa (Thymelaeceae). Their structures were elucidated by 1D and 2D-NMR spectroscopy, as well as HR-ESI-MS data. Compounds 1 and 2 were evaluated for inhibitory activities against acetylcholinesterase and compound 2 showed a moderate activity with 31% inhibition.

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