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Five new eudesmane-type sesquiterpenoids from Chinese agarwood induced by artificial holing

文献类型： 外文期刊

作者： Li, Wei 1 ; Cai, Cai-Hong 1 ; Guo, Zhi-Kai 1 ; Wang, Hao 1 ; Zuo, Wen-Jian 1 ; Dong, Wen-Hua 1 ; Mei, Wen-Li 2 ; Dai, Hao 1 ;

作者机构： 1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Key Lab Biol & Genet Resources Trop Crops, Minist Agr, Haikou 571101, Hainan, Peoples R China

2.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Key Lab Biol & Genet Resources Trop Crops, Minis

关键词： Agarwood induced by artificial holing;Aquilaria sinensis (Lour.) Gilg;Thymelaeaceae;Sesquiterpenoids;Antibacterial activities;AChE inhibitory activities

期刊名称：FITOTERAPIA （ 影响因子：2.882； 五年影响因子：3.202 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： Five new eudesmane-type sesquiterpenoids (1-5), along with six known ones (6-11), were isolated from Chinese agarwood induced by artificial holing originating from Aquilaria sinensis (Lour.) Gilg (Thymelaeaceae). The structures of the new sesquiterpenoids were established by spectroscopic methods including UV, IR, MS, 1D, and 2D NMR. Compounds 1, 3, 6 and 7 exhibited antibacterial activities against both Staphylococcus aureus and Ralstonia solanacearum, and compound 5 only showed an inhibitory activity towards S. aureus. Compounds 1, 6, 7 and 10 showed weak acetylcholinesterase inhibitory activity. (C) 2014 Elsevier B.V. All rights reserved.

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