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Two new phragmalin-type limonoids from stems of Chukrasia tabularis

文献类型： 外文期刊

作者： Peng, Jun-Lin 1 ; Jun-Wang 1 ; Kong, Fan-Dong 1 ; Liu, Zi-Qi; Wang, Pei 1 ; Gai, Cui-Juan 1 ; Jiang, Bei; Mei, Wen- 1 ;

作者机构： 1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Minist Agr, Key Lab Biol & Genet Resources Trop Crops, Haikou 571101, Peoples R China

2.Dali Univ

关键词： Chukrasia tabularis;Phragmalin;Limonoid;alpha-Glucosidase activity

期刊名称：PHYTOCHEMISTRY LETTERS （ 影响因子：1.679； 五年影响因子：1.861 ）

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收录情况： SCI

摘要： Phytochemical investigation on the stems of Chukrasia tabularis A. Juss led to the isolation of two new phragmalin-type limonoids and three known ones. The structures of the new compounds were elucidated as Chuklarisin A (1) and Chuklarisin B (2) by spectroscopic techniques (IR, HRESIMS, 1D and 2D NMR) and comparing with published data. All the compounds were evaluated for alpha-glucosidase inhibitory activity in vitro. Compounds 2, 3, and 4 exhibited inhibitory activity against alpha-glucosidase with IC50 values of 0.96, 0.03, and 0.53 mM, respectively (acarbose as positive control, IC50 0.95 mM). (C) 2016 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.

  • 相关文献

[1]Two new phragmalin-type limonoids from Chukrasia tabularis and their alpha-glucosidase inhibitory activity. Peng, Jun-Lin,Wang, Jun,Mei, Wen-Li,Kong, Fan-Dong,Wang, Pei,Gai, Cui-Juan,Dai, Hao-Fu,Peng, Jun-Lin,Liu, Zi-Qi,Jiang, Bei.

[2]New Phragmalin-Type Limonoids from Chukrasia tabularis and Their alpha-Glucosidase Inhibitory Activity. Peng, Jun-Lin,Wang, Jun,Kong, Fan-Dong,Wang, Pei,Gai, Cui-Juan,Mei, Wen-Li,Dai, Hao-Fu,Peng, Jun-Lin,Liu, Zi-Qi,Jiang, Bei.

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