文献类型： 外文期刊
作者： Kong, Fan Dong 1 ; Zhou, Li Man 1 ; Ma, Qing Yun 1 ; Huang, Sheng Zhuo 1 ; Wang, Pei 1 ; Dai, Hao-Fu 1 ; Zhao, You-Xin 1 ;
作者机构： 1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Minist Agr, Key Lab Biol & Genet Resources Trop Crops, Haikou 571101, Peoples R China
期刊名称：PHYTOCHEMISTRY LETTERS （ 影响因子：1.679； 五年影响因子：1.861 ）
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收录情况： SCI
摘要： Five new compounds named penicillars A-E were isolated from the fermentation broth of Penicillium sp. SCS-KFD08 associated with the marine animal Sipunculus nudus from the Haikou bay of China. Their planar structures and absolute configurations were unambiguously elucidated by spectroscopic data, Mo-2(OAc)(4) induced CD spectrum analysis along with quantum ECD calculation. Among them, compounds 2 and 3, at a concentration of 50 mu g/mL, showed weak inhibitory activity against AChE with inhibition rates of 19.5% and 21.3%, respectively. (C) 2016 Phytochemical Society of Europe. Published by Elsevier Ltd. All rights reserved.
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