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2-(2-Phenylethyl)chromone Derivatives of Agarwood Originating from Gyrinops salicifolia

文献类型: 外文期刊

作者: Shao, Hang 1 ; Mei, Wen-Li 2 ; Dong, Wen-Hua 2 ; Gai, Cui-Juan 2 ; Li, Wei 2 ; Zhu, Guo-Peng 1 ; Dai, Hao-Fu 3 ;

作者机构: 1.Hainan Univ, Hort & Garden Coll, Haikou 570228, Hainan, Peoples R China

2.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Key Lab Biol & Genet Resources Trop Crops, Minist Agr, Haikou 571101, Hainan, Peoples R China

3.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Key Lab Biol & Genet Resources Trop Crops, Minist Agr,

关键词: 2-(2-phenylethyl)chromone derivative;2-(2-phenylethenyl)chromone derivative;agarwood;Gyrinops salicifolia;cytotoxicity

期刊名称:MOLECULES ( 影响因子:4.411; 五年影响因子:4.587 )

ISSN:

年卷期:

页码:

收录情况: SCI

摘要: Three new 2-(2-phenylethyl)chromone derivatives (1-3) and a new 2-(2-phenylethenyl)chromone derivative (4), together with two known 2-(2-phenylethyl)chromone derivatives (5-6), were isolated from agarwood originating from Gyrinops salicifolia Ridl. The structures of compounds 1-4 were elucidated by comprehensive spectroscopic techniques (UV, IR, 1D and 2D-NMR) and MS analysis, as well as by comparison with the literature. Compounds 1, 2, and 5 showed moderate cytotoxicity against human tumor K562, BEL-7402, and SGC-7901 cell lines with IC50 values of 5.76 to 20.1 mu M.

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