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Chemical Constituents from the Stems of Daphne holosericea (DIELS) HAMAYA

文献类型： 外文期刊

作者： Ma, Qing-Yun 1 ; Chen, Yi-Chun 2 ; Huang, Sheng-Zhuo 1 ; Kong, Fan-Dong 1 ; Zhou, Li-Man 1 ; Dai, Hao-Fu 1 ; Hua, Yan; 1 ;

作者机构： 1.Chinese Acad Trop Agr Sci, Key Lab Biol & Genet Resources Trop Crops, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China

2.Southwest Forestry Univ, Coll Forestry, Kunming 650224, Peoples R China

关键词： Daphne holosericea;Thymelaeaceae;Dapholosericol A;Dapholosericin A;AChE inhibition

期刊名称：CHEMISTRY & BIODIVERSITY （ 影响因子：2.408； 五年影响因子：2.351 ）

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收录情况： SCI

摘要： Two new compounds, one flavanol dimer dapholosericol A (1) and one tigliane diterpene dapholosericin A (2), together with ten known ones, were isolated from the AcOEt extract of Daphne holosericea (DIELS) HAMAYA. Their structures were elucidated by their spectroscopic data analysis. Compounds 1 and 2 showed moderate activities against acetylcholinesterase with inhibition ratio of 36% and 29% at a concentration of 100 mu mol/l, respectively.

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