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Chemical study of the fungus Psilocybe merdaria

文献类型： 外文期刊

作者： Yang, Ning-Ning 1 ; Ma, Qing-Yun 2 ; Huang, Sheng-Zhuo 2 ; Kong, Fan-Dong 2 ; Dai, Hao-Fu 2 ; Yu, Zhi-Fang 1 ; Zhao, Y 1 ;

作者机构： 1.Nanjing Agr Univ, Coll Food Sci & Technol, Nanjing 210095, Jiangsu, Peoples R China

2.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Key Lab Biol & Genet Resources Trop Crops, Haikou 571101, Peoples R China

关键词： Psilocybe;Psilocybe merdaria;indole alkaloids;AChE inhibitory activity

期刊名称：JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH （ 影响因子：1.569； 五年影响因子：1.598 ）

ISSN：

年卷期：

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收录情况： SCI

摘要： Chemical investigation on the cultures of the fungus Psilocybe merdaria resulted in the first isolation of 10 compounds including two new ones 11,14-dihydroxylneoechinulin E (1) and (S)-4-(4-methylpent-3-en-1-yl)-butyrolactone (2). Their structures were elucidated from the analysis of 1D and 2D NMR and MS data. Among them, compound 7 showed inhibitory activity against AChE with 20% percentage at a concentration of 50 mu g/ml.

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