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Drimane-type sesquiterpenoids from cultures of the fungus Xylaria polymorpha

文献类型： 外文期刊

作者： Yang, Ning Ning 1 ; Kong, Fan Dong 2 ; Ma, Qing Yun 2 ; Huang, Sheng Zhuo 2 ; Luo, Du Qiang; Zhou, Li Man 2 ; Dai, 1 ;

作者机构： 1.Nanjing Agr Univ, Coll Food Sci & Technol, Nanjing 210095, Jiangsu, Peoples R China

2.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Key Lab Biol & Genet Resources Trop Crops, Haikou 571101, Peoples R China

3.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol

关键词： Sesquiterpenoid;Xylaria polymorpha;X-ray diffraction analysis;Anti-AChE inhibitory activity

期刊名称：PHYTOCHEMISTRY LETTERS （ 影响因子：1.679； 五年影响因子：1.861 ）

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收录情况： SCI

摘要： Three new drimane-type sesquiterpenoids named xylariaines A-C (1-3), together with one known analogue (4), were isolated from the ethyl acetate extract of cultures of the fungus Xylaria polymorpha (Pers.: Fr.) Grer. Their structures were elucidated unambiguously by NMR and single-crystal X-ray diffraction analysis. Compounds 1 and 2 exhibited weak anti-acetylcholinesterase activities at a concentration of 50 mu g/mL with inhibition ratios of 12.4% and 18.0%, respectively. (C) 2017 Phytochemical Society of Europe. Published by Elsevier Ltd. All rights reserved.

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