Construction of quaternary ammonium chitosan-coated protein nanoparticles as novel delivery system for curcumin: Characterization, stability, antioxidant activity and bio-accessibility
文献类型： 外文期刊
作者： Liu, Qianyuan 1 ; Zhang, Qian 1 ; Jia, Feihong 1 ; Jiang, Ning 1 ; Wang, Cheng 1 ; Sun, Rongxue 1 ; Ma, Yanhong 1 ;
作者机构： 1.Jiangsu Acad Agr Sci, Inst Agr Prod Proc, Nanjing 210014, Jiangsu, Peoples R China
2.Minist Agr & Rural Affairs, Integrated Sci Res Base Preservat Storage & Proc T, Nanjing 210014, Jiangsu, Peoples R China
3.Nanjing Forestry Univ, Coll Light Ind & Food Engn, Nanjing 210037, Jiangsu, Peoples R China
关键词： Curcumin; Zein; Sodium caseinate; Quaternary ammonium chitosan; Protein -polysaccharide nanoparticles; Delivery system
期刊名称：FOOD CHEMISTRY （ 影响因子：8.5； 五年影响因子：8.2 ）
ISSN： 0308-8146
年卷期： 2024 年 455 卷
页码：
收录情况： SCI
摘要： This research aimed to develop a novel, effective, and stable delivery system based on zein (ZE), sodium caseinate (SC), and quaternary ammonium chitosan (HACC) for curcumin (CUR). The pH-driven self-assembly combined with electrostatic deposition methods were employed to construct CUR-loaded ZE-SC nanoparticles with HACC coating (ZE-SC@HACC). The optimized nanocomposite was prepared at ZE:SC:HACC:CUR mass ratios of 1:1:2:0.1, and it had encapsulation efficiency of 89.3%, average diameter of 218.2 nm, and zeta-potential of 40.7 mV. The assembly of composites and encapsulation of CUR were facilitated primarily by hydrophobic, hydrogen-bonding, and electrostatic interactions. Physicochemical stability analysis revealed that HACC coating dramatically enhanced ZE-SC nanoparticles' colloidal stability and CUR's resistance to chemical degradation. Additionally, antioxidant activity and simulated digestion results indicated that CUR-ZE-SC@HACC nanoparticles showed higher free radical scavenging capacity and bio-accessibility of CUR than CUR-ZE-SC nanoparticles and free CUR. Therefore, the ZE-SC@HACC nanocomposite is an effective and viable delivery system for CUR.
- 相关文献
作者其他论文 更多>>
-
Effects of Biodegradable Plastic Film Mulching on the Global Warming Potential, Carbon Footprint, and Economic Benefits of Garlic Production
作者：Chen, Qian;Zhu, Liqun;Hu, Naijuan;Zhang, Qian;Sun, Hongwu;Zhu, Liqun
关键词：biodegradable plastic film; greenhouse gas; garlic yield; carbon footprint; net ecosystem economic benefit
-
Ultra-Highly Stiff and Tough Shape Memory Polyurea with Unprecedented Energy Density by Precise Slight Cross-Linking
作者：Chen, Jiaoyang;Yao, Bowen;Geng, Yuhao;Xu, Jianhua;Chen, Tao;Jing, Jiajie;Fu, Jiajun;Wang, Zhifeng;Wang, Cheng
关键词：covalent and supramolecular bonds; environmental stability and recyclability; high energy density; mechanical robustness and toughness; shape memory polymers
-
Extraction of flavonoids from black mulberry wine residues and their antioxidant and anticancer activity in vitro
作者：Ma, Jian;Ma, Yanhong;Jia, Feihong;Yu, Lijun;Huang, Wuyang;Ma, Jian;Ma, Yanhong;Jia, Feihong;Wang, Yu;Li, Peng;Liang, Liya;Ma, Yanhong
关键词：Black mulberry wine residues; Flavonoids; Ultrasound -assisted enzymatic extraction; Antioxidant capacity; Anticancer; Apoptosis
-
Effect of Chinese bayberry residue on quality of Chinese quinoa ( Chenopodium quinoa Willd.) Rice wine
作者：Ma, Jian;Huang, Wuyang;Ma, Yanhong;Wen, Bo;Jia, Feihong;Ma, Jian;Ma, Yanhong;Gao, Zhiqiang;Ma, Jian;Li, Jian;Feng, Naihong;Ma, Yanhong;Wen, Bo;Jia, Feihong;Wang, Yu
关键词：Chinese quinoa rice wine; Chinese bayberry residue; Metabolism; Antioxidant; Taste trait; Aroma
-
Expression and antiviral application of exogenous lectin (griffithsin) in sweetpotatoes
作者：Liu, Shuai;Yu, Yang;Guo, Ke;Zhang, Qian;Jia, Zhaodong;Ma, Peiyong;Bian, Xiaofeng;Alfredo, Morales Rodriguez;Xie, Hao
关键词：griffithsin; sweetpotato (Ipomoea batatas (L.) Lam); sweetpotato virus disease; sweetpotato leaf curl virus; antiviral genes
-
Integrated Analysis of Transcriptome and Metabolome Reveals Differential Responses to Alternaria brassicicola Infection in Cabbage (Brassica oleracea var. capitata)
作者：Lei, Jinzhou;Liu, Zhigang;Song, Jianghua;Wang, Shenyun;Zhang, Wei;Yu, Fangwei;Ni, Meng;Li, Jianbin;Wang, Shenyun;Wang, Cheng
关键词：cabbage; Alternaria brassicicola; reactive oxygen species; jasmonic acid signaling; indolic glucosinolate biosynthesis; transcriptome; metabolome
-
The preservable effects of ultrasound-assisted alginate oligosaccharide soaking on cooked crayfish subjected to Freeze-Thaw cycles
作者：Han, Jiping;Wang, Cheng;Xiong, Lingming;Ma, Yanhong;Zhu, Yongzhi;Jiang, Ning;Han, Jiping;Gao, Ruichang;Wang, Lin;Jiang, Ning;Han, Jiping;Wang, Cheng;Xiong, Lingming;Ma, Yanhong;Zhu, Yongzhi;Jiang, Ning;Zhang, Tao
关键词：Ultrasound; Alginate Oligosaccharide; Freeze-Thaw Cycle; Crayfish; Water Retention; Myofibrillar Proteins
