文献类型： 外文期刊
作者： Yang, Hong-run 1 ; Wang, Pei 2 ; Liu, Fang-Zheng 1 ; Yuan, Jing-Zhe 2 ; Cai, Cai-Hong 2 ; Wu, Fei 2 ; Jiang, Bei 1 ; Mei, Wen-Li 2 ; Dai, Hao-Fu 1 ;
作者机构： 1.Dali Univ, Coll Pharm, Dali 671003, Peoples R China
2.Hainan Inst Trop Agr Resources, Inst Trop Biosci & Biotechnol, Chinese Acad Trop Agr Sci, Key Lab Res & Dev Nat Prod Li Folk Med Hainan Prov, Haikou, Peoples R China
3.Chinese Acad Trop Agr Sci, Hainan Inst Trop Agr Resources, Inst Trop Biosci & Biotechnol, Hainan Engn Res Ctr Agarwood, Haikou 571101, Hainan, Peoples R China
关键词： Agarwood; Aquilaria filaria; 2-(2-phenethyl)chromone dimers; Anti-inflammatory activity
期刊名称：FITOTERAPIA （ 影响因子：3.4； 五年影响因子：3.3 ）
ISSN： 0367-326X
年卷期： 2023 年 165 卷
页码：
收录情况： SCI
摘要： Four new 2-(2-phenethyl)chromone dimers (1-4) were isolated from EtOAc extract of agarwood originating from Aquilaria filaria from Philippines. Their structures were elucidated by spectroscopic analysis (1D and 2D NMR, and HRESIMS) and comparison of the experimental and computed ECD curves. Compounds 1-4 exhibited in-hibition of nitric oxide production in lipopolysaccharide-stimulated RAW264.7 cells with IC50 values in the range from 33.94 to 57.53 mu M.
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