文献类型： 外文期刊
作者： Huang, Yunzhen 1 ; Kang, Huahua 1 ; Dong, Jiawen 1 ; Li, Linlin 1 ; Zhang, Jianfeng 1 ; Sun, Junying 1 ; Zhang, Junqin 1 ;
作者机构： 1.Guangdong Acad Agr Sci, Inst Anim Hlth, Guangdong Open Lab Vet Publ Hlth,Sci Observat & E, Minist Agr,Guangdong Prov Key Lab Livestock Dis P, Baishigang Rd, Guangzhou, Guangdong, Peoples R China
关键词： Duck adenovirus (DAdV); Phylogenetic analysis; Aviadenoviruses; Sequence
期刊名称：VETERINARY MICROBIOLOGY （ 影响因子：3.293； 五年影响因子：3.599 ）
ISSN： 0378-1135
年卷期： 2020 年 247 卷
页码：
收录情况： SCI
摘要： A novel duck adenovirus, isolated from Jinding Ducks(Anas platyrhynchos domestica), was proposed to be duck adenovirus 4 (DAdV-4), extending the genus Aviadenovirus. In this study, we sequenced the central genome part from Iva2 gene to fiber gene of the DAdV-4 that is conserved in all adenovirus genera. Phylogenetic analysis and protease cleavage site analysis verified the classification of DAdV-4 in the genus Aviadenovirus. Nucleotide identity analysis showed low sequence identity between central genome part genes of DAdV-4 with that of other aviadenoviruses. The phylogenetic tree based on the full amino acid sequence of hexon and DNA polymerase showed that the DAdV-4 appeared on a relatively independent branch. Our analysis suggested that DAdV-4 is a distinct type and represents a novel species. Although DAdV-4 has not caused serious disease outbreaks among ducks yet, the virus should be considered as a potential threat to the poultry industry.
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